New prenylated benzoic acid derivatives of Piper hispidum
Three new 4-hydroxy-benzoic acid derivatives, 4-methoxy-3,5-bis-(3-hydroxy-3-methyl-1-butenyl)benzo-ate, 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid, and 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid methyl ester together with eight k...
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| Veröffentlicht in: | Pharmazie 2005-06, Vol.60 (6), p.455-457 |
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| container_title | Pharmazie |
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| creator | Friedrich, U. Siems, K. Solis, P. N. Gupta, M. P. Jenett-Siems, K. |
| description | Three new 4-hydroxy-benzoic acid derivatives, 4-methoxy-3,5-bis-(3-hydroxy-3-methyl-1-butenyl)benzo-ate, 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid, and 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid methyl ester together
with eight known compounds, have been isolated from the stems of Piper hispidum. Their structures were elucidated by a detailed spectroscopic analysis. In addition, the cytotoxicity of seven isolated compounds has been evaluated, revealing a moderate activity for three derivatives of
dillapiole. |
| format | Article |
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with eight known compounds, have been isolated from the stems of Piper hispidum. Their structures were elucidated by a detailed spectroscopic analysis. In addition, the cytotoxicity of seven isolated compounds has been evaluated, revealing a moderate activity for three derivatives of
dillapiole.</description><subject>Antineoplastic Agents, Phytogenic - isolation & purification</subject><subject>Antineoplastic Agents, Phytogenic - pharmacology</subject><subject>Benzoates - chemistry</subject><subject>Benzoates - isolation & purification</subject><subject>Benzoates - toxicity</subject><subject>Cell Line, Tumor</subject><subject>Humans</subject><subject>Latin America</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Piper - chemistry</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Leaves - chemistry</subject><subject>Protein Prenylation</subject><issn>0031-7144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMtOwzAURLMA0VL4BeQfiHQdPxIvUXlKFbCAteXY162r5iHngdqvJ6Vlyd3MXYyOZuYimQMwmuaU81ly3XVbgExmsrhKZlQolRdMzhP1ht-kjVjvd6ZHR0qsD02wxNjgiMMYRtOHETvSePIRWoxkE7o2uKG6SS692XV4e9ZF8vX0-Ll8SVfvz6_L-1UaGM_6VIgcbC4h95IyLA1wyUrFLaCywAVDxSRaWQgDRimhvPAKGEfhCqu8Q7ZI7k7cdigrdLqNoTJxr_86TIaHkyHUa6x7o7fNEOspkl43Y9DtxsTKHHQGIDT8noTzA1Kb2E9K6YR5_wcT7Il0nPO4ph4l1HICZhQKyjRMsbVDb4Zdr3sT9fqgu4n4A9Bbca0</recordid><startdate>20050601</startdate><enddate>20050601</enddate><creator>Friedrich, U.</creator><creator>Siems, K.</creator><creator>Solis, P. N.</creator><creator>Gupta, M. P.</creator><creator>Jenett-Siems, K.</creator><general>Govi-Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20050601</creationdate><title>New prenylated benzoic acid derivatives of Piper hispidum</title><author>Friedrich, U. ; Siems, K. ; Solis, P. N. ; Gupta, M. P. ; Jenett-Siems, K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i342t-5570c7607f613eba0463b94c0e9c0453e936ec685a0a9959f5f9034e5d8c9fde3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Antineoplastic Agents, Phytogenic - isolation & purification</topic><topic>Antineoplastic Agents, Phytogenic - pharmacology</topic><topic>Benzoates - chemistry</topic><topic>Benzoates - isolation & purification</topic><topic>Benzoates - toxicity</topic><topic>Cell Line, Tumor</topic><topic>Humans</topic><topic>Latin America</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Piper - chemistry</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Leaves - chemistry</topic><topic>Protein Prenylation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Friedrich, U.</creatorcontrib><creatorcontrib>Siems, K.</creatorcontrib><creatorcontrib>Solis, P. N.</creatorcontrib><creatorcontrib>Gupta, M. P.</creatorcontrib><creatorcontrib>Jenett-Siems, K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Pharmazie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Friedrich, U.</au><au>Siems, K.</au><au>Solis, P. N.</au><au>Gupta, M. P.</au><au>Jenett-Siems, K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New prenylated benzoic acid derivatives of Piper hispidum</atitle><jtitle>Pharmazie</jtitle><addtitle>Pharmazie</addtitle><date>2005-06-01</date><risdate>2005</risdate><volume>60</volume><issue>6</issue><spage>455</spage><epage>457</epage><pages>455-457</pages><issn>0031-7144</issn><abstract>Three new 4-hydroxy-benzoic acid derivatives, 4-methoxy-3,5-bis-(3-hydroxy-3-methyl-1-butenyl)benzo-ate, 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid, and 3-hydroxy-2-(1-hydroxy-1-methylethyl)-2,3-dihydrobenzofuran-5-carboxylic acid methyl ester together
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| identifier | ISSN: 0031-7144 |
| ispartof | Pharmazie, 2005-06, Vol.60 (6), p.455-457 |
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| language | eng |
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| source | MEDLINE; IngentaConnect Open Access Journals; EZB Electronic Journals Library |
| subjects | Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Benzoates - chemistry Benzoates - isolation & purification Benzoates - toxicity Cell Line, Tumor Humans Latin America Magnetic Resonance Spectroscopy Piper - chemistry Plant Extracts - chemistry Plant Leaves - chemistry Protein Prenylation |
| title | New prenylated benzoic acid derivatives of Piper hispidum |
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