Clinical Experience with Rhenium-186-Labeled Monoclonal Antibodies for Radioimmunotherapy: Results of Phase I Trials

Rhenium is a radionuclide with physical and chemical properties suitable for radioimmunotherapy. Two Phase I trials were carried out using 186Re-labeled murine monoclonal antibodies. Patients with refractory metastatic epithelial carcinoma received single doses of either 186Re-labeled intact NR-LU-1...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1992-06, Vol.33 (6), p.1099
Hauptverfasser:	Breitz, Hazel B, Weiden, Paul L, Vanderheyden, J-L, Appelbaum, Janet W, Bjorn, Michael J, Fer, Mehmet F, Wolf, Sandra B, Ratliff, Barbara A, Seiler, Christine A, Foisie, Debbie C, Fisher, Darrell R, Schroff, Robert W, Fritzberg, Alan R, Abrams, Paul G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animals Antibodies, Monoclonal - therapeutic use Drug Evaluation Female Humans Male Mice Middle Aged Neoplasms - radiotherapy Radioimmunotherapy Radioisotopes - therapeutic use Rhenium - therapeutic use
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