Tyrosine Phosphorylation of Caveolin 1 by Oxidative Stress Is Reversible and Dependent on the c-src Tyrosine Kinase but Not Mitogen-Activated Protein Kinase Pathways in Placental Artery Endothelial Cells

Acute H 2 O 2 exposure to placental artery endothelial cells induced an array of tyrosine-phosphorylated proteins, including caveolin 1 (CAV1) rapid and transient tyr 14 phosphorylated in a time- and concentration-dependent manner. Basal tyr 14 phosphorylated CAV1 was primarily located at the edges...

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