S-Adenosylhomocysteine Metabolism in Different Cell Lines: Effect of Hypoxia and Cell Density

Background/Aims: The methylation potential (MP) is defined as the ratio of S-adenosylmethionine (AdoMet) to S-adenosylhomocysteine (AdoHcy). It was shown recently that hypoxia increases AdoMet/AdoHcy ratio in HepG2 cells (Hermes et al., Exp Cell Res 294: 325-334, 2004). In the present study, we comp...

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Veröffentlicht in:Cellular physiology and biochemistry 2005-01, Vol.15 (5), p.233-244
Hauptverfasser: Hermes, Marina, von Hippel, Sandra, Osswald, Hartmut, Kloor, Doris
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Sprache:eng
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