Proximal pancreatectomy in a case of nesidioblastosis

A 19 moth-old child who presented seizures secondary to intractable hypoglycemia, fulfilling the clinical and biochemical criteria for hyperinsulinism was studied. Histopathological findings of the pancreas showed the presence of small clusters of b cell islets throughout acinar tissue near ducts, i...

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Veröffentlicht in:Gaceta médica de México 2005-03, Vol.141 (2), p.157
Hauptverfasser: Flores-Alvarado, Luis Javier, Enríquez, Sergio Sánchez, Moreno, Abraham Zepeda, Ramírez-Garcial, Sergio Alberto, Bueno-Topete, Miriam Ruth, Ayub-Ayala, Mónica, del Vázquez-López, Lucía Sagrario, Gallardo-Meza, Antonio, Nuño-Moren, Patricia, Gaspar-Barba, César Enrique
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container_issue 2
container_start_page 157
container_title Gaceta médica de México
container_volume 141
creator Flores-Alvarado, Luis Javier
Enríquez, Sergio Sánchez
Moreno, Abraham Zepeda
Ramírez-Garcial, Sergio Alberto
Bueno-Topete, Miriam Ruth
Ayub-Ayala, Mónica
del Vázquez-López, Lucía Sagrario
Gallardo-Meza, Antonio
Nuño-Moren, Patricia
Gaspar-Barba, César Enrique
description A 19 moth-old child who presented seizures secondary to intractable hypoglycemia, fulfilling the clinical and biochemical criteria for hyperinsulinism was studied. Histopathological findings of the pancreas showed the presence of small clusters of b cell islets throughout acinar tissue near ducts, in both the head and the proximal third of the body. Proximal pancreatectomy (60%) and distal pancreatic-jejunostomy (Roux-in-Y) were performed. This procedure was effective in reverting hypoglycemia and constitutes the first successful alternative treatment.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Diagnostic Techniques, Endocrine
Humans
Hyperinsulinism - diagnosis
Hyperinsulinism - etiology
Hyperinsulinism - surgery
Hypoglycemia - diagnosis
Hypoglycemia - etiology
Hypoglycemia - surgery
Infant
Male
Nesidioblastosis - complications
Nesidioblastosis - pathology
Nesidioblastosis - surgery
Pancreas - pathology
Pancreas - surgery
Pancreatectomy - methods
Treatment Outcome
title Proximal pancreatectomy in a case of nesidioblastosis
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