Quercetin-Dependent Inhibition of Nitration Induced by Peroxidase/H2O2/Nitrite Systems in Human Saliva and Characterization of an Oxidation Product of Quercetin Formed during the Inhibition

Local pH in the oral cavity can decrease to below 7 at the site where acid-producing bacteria are proliferating. Effects of pH on nitration of 4-hydroxyphenylacetic acid were studied using dialyzed human saliva. Dialyzed saliva nitrated 4-hydroxyphenylacetic acid to 4-hydroxy-3-nitrophenylacetic aci...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2005-05, Vol.53 (9), p.3265-3272
Hauptverfasser:	Hirota, Sachiko, Takahama, Umeo, Ly, Tram Ngoc, Yamauchi, Ryo
Format:	Artikel
Sprache:	eng
Schlagworte:	4-hydroxy-3-nitrophenylacetic acid 4-hydroxyphenylacetic acid chemical reactions free radicals Humans hydrogen peroxide Hydrogen Peroxide - metabolism Hydrogen-Ion Concentration nitrates Nitrates - metabolism nitration Nitrites - metabolism nitrogen dioxide organic acids and salts Oxidation-Reduction peroxidase Peroxidase - metabolism Phenylacetates - metabolism quercetin Quercetin - chemistry Quercetin - metabolism Quercetin - pharmacology reaction inhibition saliva Saliva - metabolism
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