Steroid-induced Osteonecrosis in Refractory Ulcerative Colitis
We report a case of steroid-induced osteonecrosis in a patient with refractory ulcerative colitis. A 31 year-old woman presented suffering from refractory ulcerative colitis. She had been treated by prednisolone for ten years. Sharp pain and swelling appeared suddenly in her right knee. Conventional...
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| Veröffentlicht in: | FUKUOKA ACTA MEDICA 2005, Vol.96 (1), p.5-10 |
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| creator | Ito, Kenichi Inuo-Nakayama, Mieko Matsumoto, Masahiro Kubokawa, Masaru Sadamoto, Yojiro Kubo, Hiroaki Tanaka, Munehiro Harada, Naohiko Torigoshi, Kiyoyuki Hirakawa, Masakazu Nawata, Hajime |
| description | We report a case of steroid-induced osteonecrosis in a patient with refractory ulcerative colitis. A 31 year-old woman presented suffering from refractory ulcerative colitis. She had been treated by prednisolone for ten years. Sharp pain and swelling appeared suddenly in her right knee. Conventional radiography revealed neither osteoporosis nor a fracture. However, magnetic resonance imaging by T1-, T2- and T2*-weighted images revealed irregular heterogeneous areas of low- and high-intensity in her right femur and tibia. For a precise early diagnosis of osteonecrosis, bone magnetic resonance imaging was found to be an excellent diagnostic tool. |
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A 31 year-old woman presented suffering from refractory ulcerative colitis. She had been treated by prednisolone for ten years. Sharp pain and swelling appeared suddenly in her right knee. Conventional radiography revealed neither osteoporosis nor a fracture. However, magnetic resonance imaging by T1-, T2- and T2*-weighted images revealed irregular heterogeneous areas of low- and high-intensity in her right femur and tibia. For a precise early diagnosis of osteonecrosis, bone magnetic resonance imaging was found to be an excellent diagnostic tool.</description><identifier>ISSN: 0016-254X</identifier><identifier>PMID: 15839063</identifier><language>eng</language><publisher>Japan: Fukuoka Medical Association</publisher><subject>Adult ; Anti-Inflammatory Agents - adverse effects ; Colitis, Ulcerative - drug therapy ; Female ; Humans ; Magnetic Resonance Imaging ; Osteonecrosis - diagnosis ; Osteonecrosis - drug therapy ; Prednisolone - adverse effects ; Tomography, X-Ray Computed</subject><ispartof>FUKUOKA ACTA MEDICA, 2005, Vol.96 (1), p.5-10</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15839063$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ito, Kenichi</creatorcontrib><creatorcontrib>Inuo-Nakayama, Mieko</creatorcontrib><creatorcontrib>Matsumoto, Masahiro</creatorcontrib><creatorcontrib>Kubokawa, Masaru</creatorcontrib><creatorcontrib>Sadamoto, Yojiro</creatorcontrib><creatorcontrib>Kubo, Hiroaki</creatorcontrib><creatorcontrib>Tanaka, Munehiro</creatorcontrib><creatorcontrib>Harada, Naohiko</creatorcontrib><creatorcontrib>Torigoshi, Kiyoyuki</creatorcontrib><creatorcontrib>Hirakawa, Masakazu</creatorcontrib><creatorcontrib>Nawata, Hajime</creatorcontrib><creatorcontrib>Department of Clinical Radiology</creatorcontrib><creatorcontrib>Department of Medicine and Bioregulatory Science</creatorcontrib><creatorcontrib>Kyushu University</creatorcontrib><creatorcontrib>Department of Orthopedics</creatorcontrib><creatorcontrib>Graduate School of Medical Sciences</creatorcontrib><title>Steroid-induced Osteonecrosis in Refractory Ulcerative Colitis</title><title>FUKUOKA ACTA MEDICA</title><addtitle>Fukuoka Igaku Zasshi</addtitle><description>We report a case of steroid-induced osteonecrosis in a patient with refractory ulcerative colitis. A 31 year-old woman presented suffering from refractory ulcerative colitis. She had been treated by prednisolone for ten years. Sharp pain and swelling appeared suddenly in her right knee. Conventional radiography revealed neither osteoporosis nor a fracture. However, magnetic resonance imaging by T1-, T2- and T2*-weighted images revealed irregular heterogeneous areas of low- and high-intensity in her right femur and tibia. For a precise early diagnosis of osteonecrosis, bone magnetic resonance imaging was found to be an excellent diagnostic tool.</description><subject>Adult</subject><subject>Anti-Inflammatory Agents - adverse effects</subject><subject>Colitis, Ulcerative - drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Osteonecrosis - diagnosis</subject><subject>Osteonecrosis - drug therapy</subject><subject>Prednisolone - adverse effects</subject><subject>Tomography, X-Ray Computed</subject><issn>0016-254X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1T19LwzAczIPixtxXkH6Bwi9JkyYvggynwmCgDnwr-fMrZOuakbTCvr3VuYfjOO447m7IHIDKkonqa0aWOQcLwBjVjKo7MqNCcQ2Sz8njx4ApBl-G3o8OfbHNA8YeXYo55CL0xTu2ybghpnOx6xwmM4RvLFaxC0PI9-S2NV3G5T8vyG79_Ll6LTfbl7fV06bcMwVDqSrVAm19xbRz1jFOueEc0Fe18tIaITUyrySva40UnKslIngEYa11ivEFebj0nkZ7RN-cUjiadG6uR6bA-hKY3OBMF_su9Njs45j6aVjjD6IdD2NsGIBoALQEOhGb8KcpaMp_8QMr4Fsl</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Ito, Kenichi</creator><creator>Inuo-Nakayama, Mieko</creator><creator>Matsumoto, Masahiro</creator><creator>Kubokawa, Masaru</creator><creator>Sadamoto, Yojiro</creator><creator>Kubo, Hiroaki</creator><creator>Tanaka, Munehiro</creator><creator>Harada, Naohiko</creator><creator>Torigoshi, Kiyoyuki</creator><creator>Hirakawa, Masakazu</creator><creator>Nawata, Hajime</creator><general>Fukuoka Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>2005</creationdate><title>Steroid-induced Osteonecrosis in Refractory Ulcerative Colitis</title><author>Ito, Kenichi ; Inuo-Nakayama, Mieko ; Matsumoto, Masahiro ; Kubokawa, Masaru ; Sadamoto, Yojiro ; Kubo, Hiroaki ; Tanaka, Munehiro ; Harada, Naohiko ; Torigoshi, Kiyoyuki ; Hirakawa, Masakazu ; Nawata, Hajime</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j280t-848f01fd429ccbc2313a330ed478d6ba569e2d863779e10cc76ee0de05bbbc823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Anti-Inflammatory Agents - adverse effects</topic><topic>Colitis, Ulcerative - drug therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Osteonecrosis - diagnosis</topic><topic>Osteonecrosis - drug therapy</topic><topic>Prednisolone - adverse effects</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ito, Kenichi</creatorcontrib><creatorcontrib>Inuo-Nakayama, Mieko</creatorcontrib><creatorcontrib>Matsumoto, Masahiro</creatorcontrib><creatorcontrib>Kubokawa, Masaru</creatorcontrib><creatorcontrib>Sadamoto, Yojiro</creatorcontrib><creatorcontrib>Kubo, Hiroaki</creatorcontrib><creatorcontrib>Tanaka, Munehiro</creatorcontrib><creatorcontrib>Harada, Naohiko</creatorcontrib><creatorcontrib>Torigoshi, Kiyoyuki</creatorcontrib><creatorcontrib>Hirakawa, Masakazu</creatorcontrib><creatorcontrib>Nawata, Hajime</creatorcontrib><creatorcontrib>Department of Clinical Radiology</creatorcontrib><creatorcontrib>Department of Medicine and Bioregulatory Science</creatorcontrib><creatorcontrib>Kyushu University</creatorcontrib><creatorcontrib>Department of Orthopedics</creatorcontrib><creatorcontrib>Graduate School of Medical Sciences</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>FUKUOKA ACTA MEDICA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ito, Kenichi</au><au>Inuo-Nakayama, Mieko</au><au>Matsumoto, Masahiro</au><au>Kubokawa, Masaru</au><au>Sadamoto, Yojiro</au><au>Kubo, Hiroaki</au><au>Tanaka, Munehiro</au><au>Harada, Naohiko</au><au>Torigoshi, Kiyoyuki</au><au>Hirakawa, Masakazu</au><au>Nawata, Hajime</au><aucorp>Department of Clinical Radiology</aucorp><aucorp>Department of Medicine and Bioregulatory Science</aucorp><aucorp>Kyushu University</aucorp><aucorp>Department of Orthopedics</aucorp><aucorp>Graduate School of Medical Sciences</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Steroid-induced Osteonecrosis in Refractory Ulcerative Colitis</atitle><jtitle>FUKUOKA ACTA MEDICA</jtitle><addtitle>Fukuoka Igaku Zasshi</addtitle><date>2005</date><risdate>2005</risdate><volume>96</volume><issue>1</issue><spage>5</spage><epage>10</epage><pages>5-10</pages><issn>0016-254X</issn><abstract>We report a case of steroid-induced osteonecrosis in a patient with refractory ulcerative colitis. A 31 year-old woman presented suffering from refractory ulcerative colitis. She had been treated by prednisolone for ten years. Sharp pain and swelling appeared suddenly in her right knee. Conventional radiography revealed neither osteoporosis nor a fracture. However, magnetic resonance imaging by T1-, T2- and T2*-weighted images revealed irregular heterogeneous areas of low- and high-intensity in her right femur and tibia. For a precise early diagnosis of osteonecrosis, bone magnetic resonance imaging was found to be an excellent diagnostic tool.</abstract><cop>Japan</cop><pub>Fukuoka Medical Association</pub><pmid>15839063</pmid><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | MEDLINE; Open Access Titles of Japan; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Anti-Inflammatory Agents - adverse effects Colitis, Ulcerative - drug therapy Female Humans Magnetic Resonance Imaging Osteonecrosis - diagnosis Osteonecrosis - drug therapy Prednisolone - adverse effects Tomography, X-Ray Computed |
| title | Steroid-induced Osteonecrosis in Refractory Ulcerative Colitis |
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