A case of vanishing bile duct syndrome associated with hypersensitivity to allopurinol
Allopurinol is frequently used for the treatment of hyperuricemia and gout. Sometimes, a life-threatening reaction develops, as is illustrated by the following case report. We describe a 60-year-old male patient who was treated with allopurinol because of asymptomatic hyperuricemia, and he was prese...
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Veröffentlicht in: | The Korean journal of hepatology 2005-03, Vol.11 (1), p.80 |
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container_title | The Korean journal of hepatology |
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creator | Choi, Seong Ho Yang, Soo Hyun Song, Young Bong Kim, Hye Jin Seo, Yeoung Tae Choi, Dong Seog Moon, Kyoung Hyoub Byun, Jong Hoon Yu, Eun Sil |
description | Allopurinol is frequently used for the treatment of hyperuricemia and gout. Sometimes, a life-threatening reaction develops, as is illustrated by the following case report. We describe a 60-year-old male patient who was treated with allopurinol because of asymptomatic hyperuricemia, and he was presented with fever, skin rash, eosinophilia, worsening renal function and vanishing bile duct syndrome. In this report, we discussed vanishing bile duct syndrome as a serious side effect of allopurinol, and we briefly reviewed the etiology, prevention, and treatment modalities for vanishing bile duct syndrome. |
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Sometimes, a life-threatening reaction develops, as is illustrated by the following case report. We describe a 60-year-old male patient who was treated with allopurinol because of asymptomatic hyperuricemia, and he was presented with fever, skin rash, eosinophilia, worsening renal function and vanishing bile duct syndrome. 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Sometimes, a life-threatening reaction develops, as is illustrated by the following case report. We describe a 60-year-old male patient who was treated with allopurinol because of asymptomatic hyperuricemia, and he was presented with fever, skin rash, eosinophilia, worsening renal function and vanishing bile duct syndrome. In this report, we discussed vanishing bile duct syndrome as a serious side effect of allopurinol, and we briefly reviewed the etiology, prevention, and treatment modalities for vanishing bile duct syndrome.</description><subject>Allopurinol - adverse effects</subject><subject>Bile Duct Diseases - etiology</subject><subject>Bile Duct Diseases - pathology</subject><subject>Drug Hypersensitivity - complications</subject><subject>Gout Suppressants - adverse effects</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><issn>1738-222X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tKxDAYRrNQnHH0FSQvUMi9meUweIMBNyruhr_JHxtpm9KkI317FfVbnLM78J2RNa-lrYQQbytymfMHY1Ixvb0gK65r-7M1ed1RBxlpCvQEQ8xtHN5pEzukfnaF5mXwU-qRQs7JRSjo6WcsLW2XEaeMQ44lnmJZaEkUui6N8xSH1F2R8wBdxus_b8jL3e3z_qE6PN0_7neHauRClSoIjcGhqtW2llgrZzn_plfGM2bBSQnBAofAtNHBaKMkKqtQa28UNkZuyM1vd5ybHv1xnGIP03L8Pyi_AGUwTV8</recordid><startdate>200503</startdate><enddate>200503</enddate><creator>Choi, Seong Ho</creator><creator>Yang, Soo Hyun</creator><creator>Song, Young Bong</creator><creator>Kim, Hye Jin</creator><creator>Seo, Yeoung Tae</creator><creator>Choi, Dong Seog</creator><creator>Moon, Kyoung Hyoub</creator><creator>Byun, Jong Hoon</creator><creator>Yu, Eun Sil</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200503</creationdate><title>A case of vanishing bile duct syndrome associated with hypersensitivity to allopurinol</title><author>Choi, Seong Ho ; Yang, Soo Hyun ; Song, Young Bong ; Kim, Hye Jin ; Seo, Yeoung Tae ; Choi, Dong Seog ; Moon, Kyoung Hyoub ; Byun, Jong Hoon ; Yu, Eun Sil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-f25efce474973e74c81174cd46d008ac33af8a1af0565f65643e484e55d64eb63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2005</creationdate><topic>Allopurinol - adverse effects</topic><topic>Bile Duct Diseases - etiology</topic><topic>Bile Duct Diseases - pathology</topic><topic>Drug Hypersensitivity - complications</topic><topic>Gout Suppressants - adverse effects</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><toplevel>online_resources</toplevel><creatorcontrib>Choi, Seong Ho</creatorcontrib><creatorcontrib>Yang, Soo Hyun</creatorcontrib><creatorcontrib>Song, Young Bong</creatorcontrib><creatorcontrib>Kim, Hye Jin</creatorcontrib><creatorcontrib>Seo, Yeoung Tae</creatorcontrib><creatorcontrib>Choi, Dong Seog</creatorcontrib><creatorcontrib>Moon, Kyoung Hyoub</creatorcontrib><creatorcontrib>Byun, Jong Hoon</creatorcontrib><creatorcontrib>Yu, Eun Sil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>The Korean journal of hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Choi, Seong Ho</au><au>Yang, Soo Hyun</au><au>Song, Young Bong</au><au>Kim, Hye Jin</au><au>Seo, Yeoung Tae</au><au>Choi, Dong Seog</au><au>Moon, Kyoung Hyoub</au><au>Byun, Jong Hoon</au><au>Yu, Eun Sil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of vanishing bile duct syndrome associated with hypersensitivity to allopurinol</atitle><jtitle>The Korean journal of hepatology</jtitle><addtitle>Korean J Hepatol</addtitle><date>2005-03</date><risdate>2005</risdate><volume>11</volume><issue>1</issue><spage>80</spage><pages>80-</pages><issn>1738-222X</issn><abstract>Allopurinol is frequently used for the treatment of hyperuricemia and gout. Sometimes, a life-threatening reaction develops, as is illustrated by the following case report. We describe a 60-year-old male patient who was treated with allopurinol because of asymptomatic hyperuricemia, and he was presented with fever, skin rash, eosinophilia, worsening renal function and vanishing bile duct syndrome. In this report, we discussed vanishing bile duct syndrome as a serious side effect of allopurinol, and we briefly reviewed the etiology, prevention, and treatment modalities for vanishing bile duct syndrome.</abstract><cop>Korea (South)</cop><pmid>15788888</pmid></addata></record> |
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subjects | Allopurinol - adverse effects Bile Duct Diseases - etiology Bile Duct Diseases - pathology Drug Hypersensitivity - complications Gout Suppressants - adverse effects Humans Male Middle Aged |
title | A case of vanishing bile duct syndrome associated with hypersensitivity to allopurinol |
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