Potential validity of thermolabile drugs outside the preservation conditions recommended by the manufacturer
Hospital pharmacists, according to the Ley del Medicamento 25/1990 of 20th December, should ensure appropriate drug preservation within the Pharmacy Department and in hospital stocks. The storage and preservation of thermolabile drugs according to manufacturer recommendations guarantees stability an...
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| Veröffentlicht in: | Farmacia hospitalaria 2004-11, Vol.28 (6), p.440 |
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| container_title | Farmacia hospitalaria |
| container_volume | 28 |
| creator | Cuervas-Mons Vendrell, M Fernández Prieto, M Sánchez Sánchez, M T Maestre Fullana, M A Abad Lecha, E Salvador Palacios, A de Frutos Soto, A |
| description | Hospital pharmacists, according to the Ley del Medicamento 25/1990 of 20th December, should ensure appropriate drug preservation within the Pharmacy Department and in hospital stocks. The storage and preservation of thermolabile drugs according to manufacturer recommendations guarantees stability and optimal use conditions until the expiration date. Cold chain disruption may significantly affect the activity and toxicity of these drugs. Pharmacists should make quick decisions in case of cold chain-related events, hence the relevance of up-to-date information on stability under temperatures differing from those recommended. A review of the information available on the stability of drugs commonly used in the hospital setting that require a fridge for storage has been carried out. |
| format | Article |
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The storage and preservation of thermolabile drugs according to manufacturer recommendations guarantees stability and optimal use conditions until the expiration date. Cold chain disruption may significantly affect the activity and toxicity of these drugs. Pharmacists should make quick decisions in case of cold chain-related events, hence the relevance of up-to-date information on stability under temperatures differing from those recommended. A review of the information available on the stability of drugs commonly used in the hospital setting that require a fridge for storage has been carried out.</description><identifier>ISSN: 1130-6343</identifier><identifier>PMID: 15628947</identifier><language>spa</language><publisher>Spain</publisher><subject>Drug Stability ; Drug Storage - standards ; Humans ; Pharmaceutical Preparations - standards ; Pharmacology, Clinical - standards ; Pharmacy Service, Hospital ; Preservation, Biological - standards ; Refrigeration ; Temperature</subject><ispartof>Farmacia hospitalaria, 2004-11, Vol.28 (6), p.440</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15628947$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cuervas-Mons Vendrell, M</creatorcontrib><creatorcontrib>Fernández Prieto, M</creatorcontrib><creatorcontrib>Sánchez Sánchez, M T</creatorcontrib><creatorcontrib>Maestre Fullana, M A</creatorcontrib><creatorcontrib>Abad Lecha, E</creatorcontrib><creatorcontrib>Salvador Palacios, A</creatorcontrib><creatorcontrib>de Frutos Soto, A</creatorcontrib><title>Potential validity of thermolabile drugs outside the preservation conditions recommended by the manufacturer</title><title>Farmacia hospitalaria</title><addtitle>Farm Hosp</addtitle><description>Hospital pharmacists, according to the Ley del Medicamento 25/1990 of 20th December, should ensure appropriate drug preservation within the Pharmacy Department and in hospital stocks. The storage and preservation of thermolabile drugs according to manufacturer recommendations guarantees stability and optimal use conditions until the expiration date. Cold chain disruption may significantly affect the activity and toxicity of these drugs. Pharmacists should make quick decisions in case of cold chain-related events, hence the relevance of up-to-date information on stability under temperatures differing from those recommended. A review of the information available on the stability of drugs commonly used in the hospital setting that require a fridge for storage has been carried out.</description><subject>Drug Stability</subject><subject>Drug Storage - standards</subject><subject>Humans</subject><subject>Pharmaceutical Preparations - standards</subject><subject>Pharmacology, Clinical - standards</subject><subject>Pharmacy Service, Hospital</subject><subject>Preservation, Biological - standards</subject><subject>Refrigeration</subject><subject>Temperature</subject><issn>1130-6343</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j9tqAyEYhL1oadK0r1B8gYVdXdf1soSeINBe5D6o_29r0XVRN5C3b3q6moH5ZmAuyLrreNsMvOcrcl3KZ9sKJll3RVadGNioerkm4S1VnKrXgR518ODriSZH6wfmmII2PiCFvLwXmpZaPOB3ROeMBfNRV58matN0rp1doRltihEnQKDm9INGPS1O27pkzDfk0ulQ8PZPN2T_-LDfPje716eX7f2umUUvGyOl7rthhAGc5QJQgFLadIyPrW0Vs9YASC4NKGOcaNFpVGpklomeWzPwDbn7nZ0XExEOc_ZR59Ph_zX_AuMlVrA</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Cuervas-Mons Vendrell, M</creator><creator>Fernández Prieto, M</creator><creator>Sánchez Sánchez, M T</creator><creator>Maestre Fullana, M A</creator><creator>Abad Lecha, E</creator><creator>Salvador Palacios, A</creator><creator>de Frutos Soto, A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200411</creationdate><title>Potential validity of thermolabile drugs outside the preservation conditions recommended by the manufacturer</title><author>Cuervas-Mons Vendrell, M ; Fernández Prieto, M ; Sánchez Sánchez, M T ; Maestre Fullana, M A ; Abad Lecha, E ; Salvador Palacios, A ; de Frutos Soto, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p547-b77a4168d6dfc35de5d99ab12380c092ccbdd737bd9bbf50efae9982c2543cb63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2004</creationdate><topic>Drug Stability</topic><topic>Drug Storage - standards</topic><topic>Humans</topic><topic>Pharmaceutical Preparations - standards</topic><topic>Pharmacology, Clinical - standards</topic><topic>Pharmacy Service, Hospital</topic><topic>Preservation, Biological - standards</topic><topic>Refrigeration</topic><topic>Temperature</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cuervas-Mons Vendrell, M</creatorcontrib><creatorcontrib>Fernández Prieto, M</creatorcontrib><creatorcontrib>Sánchez Sánchez, M T</creatorcontrib><creatorcontrib>Maestre Fullana, M A</creatorcontrib><creatorcontrib>Abad Lecha, E</creatorcontrib><creatorcontrib>Salvador Palacios, A</creatorcontrib><creatorcontrib>de Frutos Soto, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Farmacia hospitalaria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cuervas-Mons Vendrell, M</au><au>Fernández Prieto, M</au><au>Sánchez Sánchez, M T</au><au>Maestre Fullana, M A</au><au>Abad Lecha, E</au><au>Salvador Palacios, A</au><au>de Frutos Soto, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potential validity of thermolabile drugs outside the preservation conditions recommended by the manufacturer</atitle><jtitle>Farmacia hospitalaria</jtitle><addtitle>Farm Hosp</addtitle><date>2004-11</date><risdate>2004</risdate><volume>28</volume><issue>6</issue><spage>440</spage><pages>440-</pages><issn>1130-6343</issn><abstract>Hospital pharmacists, according to the Ley del Medicamento 25/1990 of 20th December, should ensure appropriate drug preservation within the Pharmacy Department and in hospital stocks. The storage and preservation of thermolabile drugs according to manufacturer recommendations guarantees stability and optimal use conditions until the expiration date. Cold chain disruption may significantly affect the activity and toxicity of these drugs. Pharmacists should make quick decisions in case of cold chain-related events, hence the relevance of up-to-date information on stability under temperatures differing from those recommended. A review of the information available on the stability of drugs commonly used in the hospital setting that require a fridge for storage has been carried out.</abstract><cop>Spain</cop><pmid>15628947</pmid></addata></record> |
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| identifier | ISSN: 1130-6343 |
| ispartof | Farmacia hospitalaria, 2004-11, Vol.28 (6), p.440 |
| issn | 1130-6343 |
| language | spa |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Drug Stability Drug Storage - standards Humans Pharmaceutical Preparations - standards Pharmacology, Clinical - standards Pharmacy Service, Hospital Preservation, Biological - standards Refrigeration Temperature |
| title | Potential validity of thermolabile drugs outside the preservation conditions recommended by the manufacturer |
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