Sequential Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 during DMBA-induced Hamster Buccal Pouch Carcinogenesis

Background: Although it is known that iNOS and COX-2 are abundantly expressed in oral premalignant and malignant lesions, respectively, the interaction between iNOS and COX-2 has not been extensively studied. The purpose of this study was to examine the alteration of the iNOS and COX-2 expression le...

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Veröffentlicht in:	In vivo (Athens) 2004-09, Vol.18 (5), p.609
Hauptverfasser:	Kim, Soo-A, Ahn, Sang-Gun, Kim, Do Kyung, Kim, Su Gwan, Lee, Sang Ho, Kim, Jin, Yoon, Jung Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene - toxicity Animals Biomarkers, Tumor - metabolism Carcinogens - toxicity Carcinoma in Situ - chemically induced Carcinoma in Situ - enzymology Carcinoma in Situ - pathology Carcinoma, Squamous Cell - chemically induced Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - pathology Cricetinae Cyclooxygenase 2 Disease Models, Animal Immunoenzyme Techniques Isoenzymes - metabolism Male Mesocricetus Mouth Neoplasms - chemically induced Mouth Neoplasms - enzymology Mouth Neoplasms - pathology Nitric Oxide Synthase - biosynthesis Nitric Oxide Synthase Type II Precancerous Conditions - chemically induced Precancerous Conditions - enzymology Precancerous Conditions - pathology Prostaglandin-Endoperoxide Synthases - metabolism
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