Long-term acetaminophen (paracetamol) treatment causes liver and kidney ultra-structural changes during rat pregnancy

Acetaminophen (paracetamol) is an analgesic-antipyretic drug virtually devoid of typical anti-inflammatory activity and hence free of some of the side-effects of aspirin and related agents (e.g. gastric erosion and bleeding complications). The worldwide use of paracetamol as a household analgesic, i...

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Veröffentlicht in:	Clinical and experimental obstetrics & gynecology 2004, Vol.31 (3), p.221
Hauptverfasser:	Neto, J Andalaft, Oliveira-Filho, R M, Simões, M J, Soares, Jr, J M, Kulay, Jr, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - toxicity Analgesics, Non-Narcotic - toxicity Animals Drug Administration Schedule Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - ultrastructure Female Hepatocytes - pathology Kidney - drug effects Kidney - pathology Kidney - ultrastructure Liver - drug effects Liver - pathology Liver - ultrastructure Microscopy Necrosis Pregnancy Rats Rats, Wistar
Online-Zugang:	Volltext
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