SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents

1 Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio 45267-0576; and 2 Sucampo Pharmaceuticals, Inc., Bethesda, Maryland 20814 Submitted 26 November 2003 ; accepted in final form 21 June 2004 ABSTRACT The purpose of this study was to determine the mechanism o...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2004-11, Vol.287 (5), p.C1173-C1183
Hauptverfasser:	Cuppoletti, John, Malinowska, Danuta H, Tewari, Kirti P, Li, Qiu-ju, Sherry, Ann M, Patchen, Myra L, Ueno, Ryuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Northern Chloride Channels - drug effects Chloride Channels - metabolism Chlorides - metabolism Cystic Fibrosis Transmembrane Conductance Regulator Dose-Response Relationship, Drug Fatty Acids - pharmacology Humans In Situ Hybridization Intestines - drug effects Intestines - metabolism Ion Transport - drug effects Membrane Potentials - drug effects Membrane Potentials - physiology Microscopy, Confocal Patch-Clamp Techniques Rabbits Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis
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