The UbcH8 Ubiquitin E2 Enzyme Is also the E2 Enzyme for ISG15, an IFN-α/β-Induced Ubiquitin-Like Protein

Ubiquitin- (Ub) like proteins (Ubls) are conjugated to their targets by an enzymatic cascade involving an E1 activating enzyme, an E2 conjugating enzyme, and in some cases an E3 ligase. ISG15 is a Ubl that is conjugated to cellular proteins after IFN-α/β stimulation. Although the E1 enzyme for ISG15...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-05, Vol.101 (20), p.7578-7582
Hauptverfasser:	Zhao, Chen, Beaudenon, Sylvie L., Kelley, Melissa L., Waddell, M. Brett, Yuan, Weiming, Schulman, Brenda A., Huibregtse, Jon M., Krug, Robert M., Howley, Peter M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological Sciences Cell extracts Cytokines - metabolism Enzyme substrates Enzymes Gels Humans Immune system Interferon-alpha - metabolism Interferon-beta - metabolism Lung - enzymology Lung - metabolism Messenger RNA Proteins Reaction products RNA Small interfering RNA Ubiquitin-Conjugating Enzymes - metabolism Ubiquitins Ubiquitins - analogs & derivatives
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!