CD81 Is an Entry Coreceptor for Hepatitis C Virus

Hepatitis C virus (HCV) envelope glycoproteins E1/E2 can pseudotype retroviral particles and efficiently mediate entry into target cells. Using this experimental system, we determined HCV tropism for different cell types. Only primary hepatocytes and one hepatoma cell line were susceptible to HCV ps...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-05, Vol.101 (19), p.7270-7274
Hauptverfasser:	Cormier, Emmanuel G., Tsamis, Fay, Kajumo, Francis, Durso, Robert J., Gardner, Jason P., Dragic, Tatjana, Danishefsky, Samuel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 cells Antigens, CD - physiology B lymphocytes Biochemistry Biological Sciences Cell Line, Tumor Cell lines Glycoproteins Hepacivirus - physiology Hepatitis Hepatitis C Hepatitis C virus Hepatocytes Humans Infections Infectious diseases Membrane Fusion - physiology Mice Receptors, Virus - physiology T lymphocytes Tetraspanin 28 Tropisms Viruses
Online-Zugang:	Volltext
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