Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2004-05, Vol.48 (5), p.1541-1547 |
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| creator | LING, Losee L JUN XIAN YIBIN XIANG MOIR, Donald T ALI, Syed BOLIN GENG JUN FAN MILLS, Debra M ARVANITES, Anthony C ORGUEIRA, Hernan ASHWELL, Mark A CARMEL, Gilles |
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| doi_str_mv | 10.1128/aac.48.5.1541-1547.2004 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.48.5.1541-1547.2004</identifier><identifier>PMID: 15105103</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents ; Bacillus subtilis ; Bacillus subtilis - drug effects ; Bacteria - drug effects ; Biological and medical sciences ; Cloning, Molecular ; Drug Evaluation, Preclinical ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) ; Enzyme Inhibitors ; Enzyme Inhibitors - chemical synthesis ; Enzyme Inhibitors - pharmacology ; Escherichia coli ; Escherichia coli - drug effects ; Escherichia coli - enzymology ; Fatty Acids - biosynthesis ; Gene Expression Regulation, Bacterial - drug effects ; Kinetics ; Lac Operon - genetics ; Mechanisms of Action: Physiological Effects ; Medical sciences ; Microbial Sensitivity Tests ; Oxidoreductases ; Oxidoreductases - antagonists & inhibitors ; Oxidoreductases - biosynthesis ; Oxidoreductases - genetics ; Pharmacology. Drug treatments ; Pyridines ; Pyridines - chemical synthesis ; Pyridines - pharmacology ; Reverse Transcriptase Polymerase Chain Reaction ; Staphylococcus - drug effects ; Staphylococcus - genetics ; Staphylococcus - metabolism ; Staphylococcus aureus ; Structure-Activity Relationship</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2004-05, Vol.48 (5), p.1541-1547</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright © 2004 American Society for Microbiology</rights><rights>Copyright © 2004, American Society for Microbiology 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a612t-934b234d2e2948d1805881310ca918b1e7afe231a8b0171272d0bff8971b85dd3</citedby><cites>FETCH-LOGICAL-a612t-934b234d2e2948d1805881310ca918b1e7afe231a8b0171272d0bff8971b85dd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC400533/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC400533/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15720623$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15105103$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LING, Losee L</creatorcontrib><creatorcontrib>JUN XIAN</creatorcontrib><creatorcontrib>YIBIN XIANG</creatorcontrib><creatorcontrib>MOIR, Donald T</creatorcontrib><creatorcontrib>ALI, Syed</creatorcontrib><creatorcontrib>BOLIN GENG</creatorcontrib><creatorcontrib>JUN FAN</creatorcontrib><creatorcontrib>MILLS, Debra M</creatorcontrib><creatorcontrib>ARVANITES, Anthony C</creatorcontrib><creatorcontrib>ORGUEIRA, Hernan</creatorcontrib><creatorcontrib>ASHWELL, Mark A</creatorcontrib><creatorcontrib>CARMEL, Gilles</creatorcontrib><title>Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Bacillus subtilis</subject><subject>Bacillus subtilis - drug effects</subject><subject>Bacteria - drug effects</subject><subject>Biological and medical sciences</subject><subject>Cloning, Molecular</subject><subject>Drug Evaluation, Preclinical</subject><subject>Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)</subject><subject>Enzyme Inhibitors</subject><subject>Enzyme Inhibitors - chemical synthesis</subject><subject>Enzyme Inhibitors - pharmacology</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Escherichia coli - enzymology</subject><subject>Fatty Acids - biosynthesis</subject><subject>Gene Expression Regulation, Bacterial - drug effects</subject><subject>Kinetics</subject><subject>Lac Operon - genetics</subject><subject>Mechanisms of Action: Physiological Effects</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Oxidoreductases</subject><subject>Oxidoreductases - antagonists & inhibitors</subject><subject>Oxidoreductases - biosynthesis</subject><subject>Oxidoreductases - genetics</subject><subject>Pharmacology. Drug treatments</subject><subject>Pyridines</subject><subject>Pyridines - chemical synthesis</subject><subject>Pyridines - pharmacology</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>Staphylococcus - drug effects</subject><subject>Staphylococcus - genetics</subject><subject>Staphylococcus - metabolism</subject><subject>Staphylococcus aureus</subject><subject>Structure-Activity Relationship</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksFu1DAQhiMEotvCK0A40FsWj2PHzoHDEhVYqRIIwdmaOE7jKmsXOylanh5HWdFyQ7LGGvv7PR7_zrLXQLYAVL5D1Fsmt3wLnEGRgthSQtiTbAOklkXF6-pptiGkqgomCTvLzmO8JSnnNXmenQEHkka5yfS-M26yvdU4We9ydF3eDBhQTybY3-ui7_O9G2xrJx_ikn1Yt3HMr5w_jsVOH8e8wRCsCfnX4CdjXf7NdLOeMJoX2bMex2henuaL7MfHq-_N5-L6y6d9s7susAI6FXXJWlqyjhpaM9mBJFxKKIForEG2YAT2hpaAsiUggArakbbvZS2glbzryovs_Xru3dweTKdTYwFHdRfsAcNRebTq3x1nB3Xj7xUjhJdl0l-e9MH_nE2c1MFGbcYRnfFzVCAEkUB5AsUK6uBjDKb_WwOIWvxRu12jmFRcLf4sQajFn6RkqxLjgapbPweXXuQ_ZK8ed_ZQ7uRjAt6eAIwaxz6g0zY-4gQlFV24Nys32Jvhlw1GpYuo9JseypZ_AM0itOE</recordid><startdate>20040501</startdate><enddate>20040501</enddate><creator>LING, Losee L</creator><creator>JUN XIAN</creator><creator>YIBIN XIANG</creator><creator>MOIR, Donald T</creator><creator>ALI, Syed</creator><creator>BOLIN GENG</creator><creator>JUN FAN</creator><creator>MILLS, Debra M</creator><creator>ARVANITES, Anthony C</creator><creator>ORGUEIRA, Hernan</creator><creator>ASHWELL, Mark A</creator><creator>CARMEL, Gilles</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>5PM</scope></search><sort><creationdate>20040501</creationdate><title>Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase</title><author>LING, Losee L ; JUN XIAN ; YIBIN XIANG ; MOIR, Donald T ; ALI, Syed ; BOLIN GENG ; JUN FAN ; MILLS, Debra M ; ARVANITES, Anthony C ; ORGUEIRA, Hernan ; ASHWELL, Mark A ; CARMEL, Gilles</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a612t-934b234d2e2948d1805881310ca918b1e7afe231a8b0171272d0bff8971b85dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Bacillus subtilis</topic><topic>Bacillus subtilis - drug effects</topic><topic>Bacteria - drug effects</topic><topic>Biological and medical sciences</topic><topic>Cloning, Molecular</topic><topic>Drug Evaluation, Preclinical</topic><topic>Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)</topic><topic>Enzyme Inhibitors</topic><topic>Enzyme Inhibitors - chemical synthesis</topic><topic>Enzyme Inhibitors - pharmacology</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Escherichia coli - enzymology</topic><topic>Fatty Acids - biosynthesis</topic><topic>Gene Expression Regulation, Bacterial - drug effects</topic><topic>Kinetics</topic><topic>Lac Operon - genetics</topic><topic>Mechanisms of Action: Physiological Effects</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Oxidoreductases</topic><topic>Oxidoreductases - antagonists & inhibitors</topic><topic>Oxidoreductases - biosynthesis</topic><topic>Oxidoreductases - genetics</topic><topic>Pharmacology. Drug treatments</topic><topic>Pyridines</topic><topic>Pyridines - chemical synthesis</topic><topic>Pyridines - pharmacology</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>Staphylococcus - drug effects</topic><topic>Staphylococcus - genetics</topic><topic>Staphylococcus - metabolism</topic><topic>Staphylococcus aureus</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LING, Losee L</creatorcontrib><creatorcontrib>JUN XIAN</creatorcontrib><creatorcontrib>YIBIN XIANG</creatorcontrib><creatorcontrib>MOIR, Donald T</creatorcontrib><creatorcontrib>ALI, Syed</creatorcontrib><creatorcontrib>BOLIN GENG</creatorcontrib><creatorcontrib>JUN FAN</creatorcontrib><creatorcontrib>MILLS, Debra M</creatorcontrib><creatorcontrib>ARVANITES, Anthony C</creatorcontrib><creatorcontrib>ORGUEIRA, Hernan</creatorcontrib><creatorcontrib>ASHWELL, Mark A</creatorcontrib><creatorcontrib>CARMEL, Gilles</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LING, Losee L</au><au>JUN XIAN</au><au>YIBIN XIANG</au><au>MOIR, Donald T</au><au>ALI, Syed</au><au>BOLIN GENG</au><au>JUN FAN</au><au>MILLS, Debra M</au><au>ARVANITES, Anthony C</au><au>ORGUEIRA, Hernan</au><au>ASHWELL, Mark A</au><au>CARMEL, Gilles</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>AAC</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2004-05-01</date><risdate>2004</risdate><volume>48</volume><issue>5</issue><spage>1541</spage><epage>1547</epage><pages>1541-1547</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>15105103</pmid><doi>10.1128/aac.48.5.1541-1547.2004</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Antimicrobial Agents and Chemotherapy, 2004-05, Vol.48 (5), p.1541-1547 |
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| source | PubMed (Medline); MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Antibiotics. Antiinfectious agents. Antiparasitic agents Bacillus subtilis Bacillus subtilis - drug effects Bacteria - drug effects Biological and medical sciences Cloning, Molecular Drug Evaluation, Preclinical Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) Enzyme Inhibitors Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - pharmacology Escherichia coli Escherichia coli - drug effects Escherichia coli - enzymology Fatty Acids - biosynthesis Gene Expression Regulation, Bacterial - drug effects Kinetics Lac Operon - genetics Mechanisms of Action: Physiological Effects Medical sciences Microbial Sensitivity Tests Oxidoreductases Oxidoreductases - antagonists & inhibitors Oxidoreductases - biosynthesis Oxidoreductases - genetics Pharmacology. Drug treatments Pyridines Pyridines - chemical synthesis Pyridines - pharmacology Reverse Transcriptase Polymerase Chain Reaction Staphylococcus - drug effects Staphylococcus - genetics Staphylococcus - metabolism Staphylococcus aureus Structure-Activity Relationship |
| title | Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase |
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