Transdermal Delivery of Ondansetron Hydrochloride: Effects of Vehicles and Penetration Enhancers

The effects of vehicles and penetration enhancers on the in vitro permeation of ondansetron hydrochloride (OS) across dorsal hairless mouse skins were investigated. Various types of vehicles, including ester, alcohol, and ether and their mixtures were used, and then a series of fatty acids and fatty...

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Veröffentlicht in:	Drug development and industrial pharmacy 2004-01, Vol.30 (2), p.187-194
Hauptverfasser:	Gwak, Hye Sun, Oh, Ik Sang, Chun, In Koo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Pharmaceutic - chemistry Adjuvants, Pharmaceutic - pharmacology Administration, Cutaneous Animals Antiemetics - administration & dosage Antiemetics - chemistry Antiemetics - pharmacokinetics Biological and medical sciences Feasibility Studies General pharmacology In Vitro Techniques Male Medical sciences Mice Mice, Hairless Ondansetron - administration & dosage Ondansetron - chemistry Ondansetron - pharmacokinetics Ondansetron hydrochloride Penetration enhancers Permeability Pharmaceutical technology. Pharmaceutical industry Pharmaceutical Vehicles - chemistry Pharmaceutical Vehicles - pharmacology Pharmacology. Drug treatments Skin Absorption Transdermal delivery Vehicles
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