Cytochrome P450 enzymes: Novel options for cancer therapeutics

The concept of overexpression of individual forms of cytochrome P 450 enzymes in tumor cells is now becoming well recognized. Indeed, a growing body of research highlights the overexpression of P 450s, particularly CYP1B1, in tumor cells as representing novel targets for anticancer therapy. The purp...

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Veröffentlicht in:	Molecular cancer therapeutics 2004-03, Vol.3 (3), p.363
Hauptverfasser:	McFadyen, Morag C E, Melvin, William T, Murray, Graeme I
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System - genetics Drug Resistance, Neoplasm Enzyme Inhibitors - pharmacology Genetic Therapy - methods Humans Immunotherapy - methods Neoplasms - drug therapy Neoplasms - enzymology Polymorphism, Genetic RNA, Messenger - metabolism
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