Induction of CDK inhibitor p21 gene as a new therapeutic strategy against pulmonary fibrosis

1 Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan; and 2 Fukuoka-Higashi National Hospital, Koga, 811-3113 Japan Submitted 30 June 2003 ; accepted in final form 12 November 2003 Alveolar epithelial cells are known to be pr...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2004-04, Vol.286 (4), p.727-L733
Hauptverfasser:	Inoshima, Ichiro, Kuwano, Kazuyoshi, Hamada, Naoki, Yoshimi, Michihiro, Maeyama, Takashige, Hagimoto, Naoki, Nakanishi, Yoichi, Hara, Nobuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Animals Cyclin-Dependent Kinase Inhibitor p21 Cyclins - genetics Epithelial Cells - pathology Epithelial Cells - physiology Gene Expression Regulation Genetic Therapy Genetic Vectors Hydroxyproline - metabolism In Situ Nick-End Labeling Male Mice Mice, Inbred C57BL Pulmonary Fibrosis - metabolism Pulmonary Fibrosis - pathology Pulmonary Fibrosis - therapy
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