Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine

The effects of crude extracts of the mushroom Agaricus blazei Murrill (Agaricaceae) on both DNA damage and placental form glutathione S-transferase (GST-P)-positive liver foci induced by diethylnitrosamine (DEN) were investigated. Six groups of adult male Wistar rats were used. For two weeks, animal...

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Veröffentlicht in:	Genetics and molecular research 2003-09, Vol.2 (3), p.295-308
Hauptverfasser:	Barbisan, L.F, Scolastici, C, Miyamoto, M, Salvadori, D.M.F, Ribeiro, L.R, Eira, A.F. da, Camargo, J.L.V. de
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricus Agaricus - chemistry Agaricus blazei Animals anticarcinogenic activity Anticarcinogenic Agents - pharmacology carcinogenesis Carcinogens Comet Assay Diethylnitrosamine DNA damage DNA Damage - drug effects Drug Screening Assays, Antitumor Glutathione Transferase - analysis Glutathione Transferase - drug effects liver Liver - drug effects Liver - enzymology Liver - pathology Liver Neoplasms, Experimental - chemically induced Liver Neoplasms, Experimental - enzymology Liver Neoplasms, Experimental - prevention & control Male mushrooms Rats Rats, Wistar
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