Perinatal Iron Deficiency Alters Apical Dendritic Growth in Hippocampal CA1 Pyramidal Neurons

Iron deficiency early in life is associated with cognitive disturbances that persist beyond the period of iron deficiency. Within cognitive processing circuitry, the hippocampus is particularly susceptible to insults during the perinatal period. During the hippocampal growth spurt, which is predomin...

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Veröffentlicht in:	Developmental neuroscience 2003-11, Vol.25 (6), p.412-420
Hauptverfasser:	Jorgenson, Lyric A., Wobken, Jane D., Georgieff, Michael K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Cell Differentiation - drug effects Cell Differentiation - physiology Dendrites - metabolism Dendrites - pathology Down-Regulation - drug effects Down-Regulation - physiology Female Fluorescent Antibody Technique Hippocampus - growth & development Hippocampus - metabolism Hippocampus - pathology Iron - deficiency Iron - pharmacology Male Microtubule-Associated Proteins - metabolism Organ Size - drug effects Organ Size - physiology Original Paper Prenatal Nutritional Physiological Phenomena - physiology Pyramidal Cells - metabolism Pyramidal Cells - pathology Rats Rats, Sprague-Dawley
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