Syphilis Serology in Men Attending the Andrology Clinic at Ga-Rankuwa Hospital
The worldwide resurgence of syphilis may have serious implications on neonatal morbidity. The aim of this study was to evaluate the seroprevalence of syphilis in men attending an infertility clinic. Blood samples from 782 males were screened using the titrated RPR and TPHA tests. If either of these...
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| Veröffentlicht in: | Archives of andrology 1992, Vol.29 (3), p.215-218 |
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| creator | Bornman, M. S. Mokonoto, J. R. Mahomed, M. F. Boomker, D. Reif, S. Crewe-brown, H. H. |
| description | The worldwide resurgence of syphilis may have serious implications on neonatal morbidity. The aim of this study was to evaluate the seroprevalence of syphilis in men attending an infertility clinic. Blood samples from 782 males were screened using the titrated RPR and TPHA tests. If either of these tests was positive, FTA-ABs IgG was performed. The RPR was positive in 63 (8%) cases. In 24 (3%) patients the titer was 1:8 with positive TPHA and FTA-Abs IgG tests and these were regarded as current infections. Thirty-nine (4.9%) cases had RPR titers 1:8 with positive specific tests. These were probably patients either treated inadequately or in the early stage of primary syphilis. In addition, 92 (12%) patients were RPR negative but TPHA and FTA positive. This was evidence of previous exposure to syphilis. The overall seropositivity in this group was 20% (155 cases). Six hundred and twenty-seven (80%) tested negative with RPR and TPHA. Syphilis may still have a major impact on health in Southern Africa. Since syphilis is significantly associated with HIV seropositivity, efforts to prevent and control syphilis may also be important in limiting the spread of HIV. |
| doi_str_mv | 10.3109/01485019208987727 |
| format | Article |
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S. ; Mokonoto, J. R. ; Mahomed, M. F. ; Boomker, D. ; Reif, S. ; Crewe-brown, H. H.</creator><creatorcontrib>Bornman, M. S. ; Mokonoto, J. R. ; Mahomed, M. F. ; Boomker, D. ; Reif, S. ; Crewe-brown, H. H.</creatorcontrib><description>The worldwide resurgence of syphilis may have serious implications on neonatal morbidity. The aim of this study was to evaluate the seroprevalence of syphilis in men attending an infertility clinic. Blood samples from 782 males were screened using the titrated RPR and TPHA tests. If either of these tests was positive, FTA-ABs IgG was performed. The RPR was positive in 63 (8%) cases. In 24 (3%) patients the titer was 1:8 with positive TPHA and FTA-Abs IgG tests and these were regarded as current infections. Thirty-nine (4.9%) cases had RPR titers 1:8 with positive specific tests. These were probably patients either treated inadequately or in the early stage of primary syphilis. In addition, 92 (12%) patients were RPR negative but TPHA and FTA positive. This was evidence of previous exposure to syphilis. The overall seropositivity in this group was 20% (155 cases). Six hundred and twenty-seven (80%) tested negative with RPR and TPHA. Syphilis may still have a major impact on health in Southern Africa. Since syphilis is significantly associated with HIV seropositivity, efforts to prevent and control syphilis may also be important in limiting the spread of HIV.</description><identifier>ISSN: 0148-5016</identifier><identifier>EISSN: 1521-0375</identifier><identifier>DOI: 10.3109/01485019208987727</identifier><identifier>PMID: 1482210</identifier><identifier>CODEN: ARANDR</identifier><language>eng</language><publisher>Philadelphia, PA: Informa UK Ltd</publisher><subject>Adult ; Bacterial diseases ; Biological and medical sciences ; Fluorescent Treponemal Antibody-Absorption Test ; Hospital ; Human bacterial diseases ; Humans ; Infectious diseases ; Male ; Male infertility ; Medical sciences ; Miscellaneous ; Serology ; Seroprevalence ; South Africa ; STD ; Syphilis ; Syphilis - diagnosis ; Syphilis - epidemiology ; Syphilis - immunology ; Treponema Immobilization Test</subject><ispartof>Archives of andrology, 1992, Vol.29 (3), p.215-218</ispartof><rights>1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1992</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-ebfc68f2ea8948e5edae6d7ce907b888e7426b1bef0033b3372b999ae555f3a43</citedby><cites>FETCH-LOGICAL-c500t-ebfc68f2ea8948e5edae6d7ce907b888e7426b1bef0033b3372b999ae555f3a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/01485019208987727$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/01485019208987727$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,780,784,4024,27923,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4465555$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1482210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bornman, M. S.</creatorcontrib><creatorcontrib>Mokonoto, J. R.</creatorcontrib><creatorcontrib>Mahomed, M. F.</creatorcontrib><creatorcontrib>Boomker, D.</creatorcontrib><creatorcontrib>Reif, S.</creatorcontrib><creatorcontrib>Crewe-brown, H. H.</creatorcontrib><title>Syphilis Serology in Men Attending the Andrology Clinic at Ga-Rankuwa Hospital</title><title>Archives of andrology</title><addtitle>Arch Androl</addtitle><description>The worldwide resurgence of syphilis may have serious implications on neonatal morbidity. The aim of this study was to evaluate the seroprevalence of syphilis in men attending an infertility clinic. Blood samples from 782 males were screened using the titrated RPR and TPHA tests. If either of these tests was positive, FTA-ABs IgG was performed. The RPR was positive in 63 (8%) cases. In 24 (3%) patients the titer was 1:8 with positive TPHA and FTA-Abs IgG tests and these were regarded as current infections. Thirty-nine (4.9%) cases had RPR titers 1:8 with positive specific tests. These were probably patients either treated inadequately or in the early stage of primary syphilis. In addition, 92 (12%) patients were RPR negative but TPHA and FTA positive. This was evidence of previous exposure to syphilis. The overall seropositivity in this group was 20% (155 cases). Six hundred and twenty-seven (80%) tested negative with RPR and TPHA. Syphilis may still have a major impact on health in Southern Africa. Since syphilis is significantly associated with HIV seropositivity, efforts to prevent and control syphilis may also be important in limiting the spread of HIV.</description><subject>Adult</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Fluorescent Treponemal Antibody-Absorption Test</subject><subject>Hospital</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Male infertility</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Serology</subject><subject>Seroprevalence</subject><subject>South Africa</subject><subject>STD</subject><subject>Syphilis</subject><subject>Syphilis - diagnosis</subject><subject>Syphilis - epidemiology</subject><subject>Syphilis - immunology</subject><subject>Treponema Immobilization Test</subject><issn>0148-5016</issn><issn>1521-0375</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN1rFDEUxYNY6rb6B_gg5EF8G5uPySSDvixLP4SqYPV5uJO5003NJmuSoex_3ym7KiL06cI9v3O49xDymrP3krP2jPHaKMZbwUxrtBb6GVlwJXjFpFbPyeJRr2ageUFOcr5jjAnVsGNyPO-F4GxBvtzstmvnXaY3mKKPtzvqAv2MgS5LwTC4cEvLGukyDAd55V1wlkKhl1B9g_Bzugd6FfPWFfAvydEIPuOrwzwlPy7Ov6-uquuvl59Wy-vKKsZKhf1oGzMKBNPWBhUOgM2gLbZM98YY1LVoet7jyJiUvZRa9G3bAiqlRgm1PCXv9rnbFH9NmEu3cdmi9xAwTrnTsq5b0cgZ5HvQpphzwrHbJreBtOs46x477P7rcPa8OYRP_QaHv459abP-9qBDtuDHBMG6_Aer62Y-U83Yxz3mwhjTBu5j8kNXYOdj-u2RT13x4R_7GsGXtYWE3V2cUpjrfeKHB8DDndg</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Bornman, M. S.</creator><creator>Mokonoto, J. R.</creator><creator>Mahomed, M. F.</creator><creator>Boomker, D.</creator><creator>Reif, S.</creator><creator>Crewe-brown, H. H.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Syphilis Serology in Men Attending the Andrology Clinic at Ga-Rankuwa Hospital</title><author>Bornman, M. S. ; Mokonoto, J. R. ; Mahomed, M. F. ; Boomker, D. ; Reif, S. ; Crewe-brown, H. H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-ebfc68f2ea8948e5edae6d7ce907b888e7426b1bef0033b3372b999ae555f3a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Fluorescent Treponemal Antibody-Absorption Test</topic><topic>Hospital</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Male infertility</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Serology</topic><topic>Seroprevalence</topic><topic>South Africa</topic><topic>STD</topic><topic>Syphilis</topic><topic>Syphilis - diagnosis</topic><topic>Syphilis - epidemiology</topic><topic>Syphilis - immunology</topic><topic>Treponema Immobilization Test</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bornman, M. S.</creatorcontrib><creatorcontrib>Mokonoto, J. R.</creatorcontrib><creatorcontrib>Mahomed, M. F.</creatorcontrib><creatorcontrib>Boomker, D.</creatorcontrib><creatorcontrib>Reif, S.</creatorcontrib><creatorcontrib>Crewe-brown, H. H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of andrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bornman, M. S.</au><au>Mokonoto, J. R.</au><au>Mahomed, M. F.</au><au>Boomker, D.</au><au>Reif, S.</au><au>Crewe-brown, H. H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Syphilis Serology in Men Attending the Andrology Clinic at Ga-Rankuwa Hospital</atitle><jtitle>Archives of andrology</jtitle><addtitle>Arch Androl</addtitle><date>1992</date><risdate>1992</risdate><volume>29</volume><issue>3</issue><spage>215</spage><epage>218</epage><pages>215-218</pages><issn>0148-5016</issn><eissn>1521-0375</eissn><coden>ARANDR</coden><abstract>The worldwide resurgence of syphilis may have serious implications on neonatal morbidity. The aim of this study was to evaluate the seroprevalence of syphilis in men attending an infertility clinic. Blood samples from 782 males were screened using the titrated RPR and TPHA tests. If either of these tests was positive, FTA-ABs IgG was performed. The RPR was positive in 63 (8%) cases. In 24 (3%) patients the titer was 1:8 with positive TPHA and FTA-Abs IgG tests and these were regarded as current infections. Thirty-nine (4.9%) cases had RPR titers 1:8 with positive specific tests. These were probably patients either treated inadequately or in the early stage of primary syphilis. In addition, 92 (12%) patients were RPR negative but TPHA and FTA positive. This was evidence of previous exposure to syphilis. The overall seropositivity in this group was 20% (155 cases). Six hundred and twenty-seven (80%) tested negative with RPR and TPHA. Syphilis may still have a major impact on health in Southern Africa. Since syphilis is significantly associated with HIV seropositivity, efforts to prevent and control syphilis may also be important in limiting the spread of HIV.</abstract><cop>Philadelphia, PA</cop><pub>Informa UK Ltd</pub><pmid>1482210</pmid><doi>10.3109/01485019208987727</doi><tpages>4</tpages></addata></record> |
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| ispartof | Archives of andrology, 1992, Vol.29 (3), p.215-218 |
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| language | eng |
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| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adult Bacterial diseases Biological and medical sciences Fluorescent Treponemal Antibody-Absorption Test Hospital Human bacterial diseases Humans Infectious diseases Male Male infertility Medical sciences Miscellaneous Serology Seroprevalence South Africa STD Syphilis Syphilis - diagnosis Syphilis - epidemiology Syphilis - immunology Treponema Immobilization Test |
| title | Syphilis Serology in Men Attending the Andrology Clinic at Ga-Rankuwa Hospital |
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