Role of cyclooxygenase in ventricular effects of adrenomedullin: is adrenomedullin a double-edged sword in sepsis?

Department of Physiology, Institute of Cardiovascular Sciences and Medicine, University of Hong Kong, Hong Kong SAR, China Submitted 10 April 2003 ; accepted in final form 22 October 2003 Adrenomedullin (ADM) is upregulated in cardiac tissue under various pathophysiological conditions. However, the...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2004-03, Vol.286 (3), p.H1034-H1042
Hauptverfasser:	Mittra, Shivani, Hyvelin, Jean-Marc, Shan, Qixian, Tang, Fai, Bourreau, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin Anesthesia Animals Blood Pressure Calcium Signaling - drug effects Calcium Signaling - physiology Cyclooxygenase 1 Cyclooxygenase 2 Isoenzymes - metabolism Lipopolysaccharides - pharmacology Male Membrane Proteins Myocardial Contraction - drug effects Myocytes, Cardiac - metabolism Peptide Fragments - pharmacology Peptides - metabolism Prostaglandin-Endoperoxide Synthases - metabolism Radioimmunoassay Rats Rats, Sprague-Dawley Sepsis - metabolism
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