Evaluation of the cumulative (repeated application) eye irritation and corneal staining potential of FD&C yellow No. 5, FD&C blue No. 1 and FD&C blue No. 1 aluminium lake

A protocol to evaluate the ocular irritation, staining, and embedding potential of FD&C colours (Yellow No. 5, Blue No. 1, Blue No. 1 Aluminium Lake) produced by repeated topical application to rabbit eyes is described. Test materials (3%, w/v in aqueous vehicle) were administered once daily, fo...

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Veröffentlicht in:	Food and chemical toxicology 1992-12, Vol.30 (12), p.1051-1055
Hauptverfasser:	GETTINGS, S. D, BLASZCAK, D. L, RODDY, M. T, CURRY, A. S, MCEWEN, G. N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzenesulfonates - toxicity Biological and medical sciences Body Weight - drug effects Conjunctiva - drug effects Cornea - drug effects Domestic and cosmetic products toxicology Female Male Medical sciences Rabbits Tartrazine - toxicity Toxicology
Online-Zugang:	Volltext
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