EFFECTS OF ENALAPRIL ON ADRIAMYCIN-INDUCED NEPHROSIS

Adriamycin induces proteinuria and glomerular changes in rats similar to those found in human focal segmental glomerulosclerosis (FSGS). Progression of this lesion may be slowed by use of angiotensin converting enzyme inhibition. To evaluate this we injected two groups of Sprague-Dawley rats with Ad...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 1992-09, Vol.6 (5), p.448-450
Hauptverfasser:	IRWIN, KC, BROUHARD, BH, SATOH, S, STOWE, NT
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Disease Models, Animal Doxorubicin Enalapril - administration & dosage Enalapril - therapeutic use Glomerular Filtration Rate - physiology Glomerulosclerosis, Focal Segmental - chemically induced Glomerulosclerosis, Focal Segmental - drug therapy Glomerulosclerosis, Focal Segmental - pathology Hemodynamics - physiology Injections, Intravenous Kidney - drug effects Kidney - physiology Life Sciences & Biomedicine Male Medical sciences Nephrology. Urinary tract diseases Nephrosis - chemically induced Nephrosis - drug therapy Organ Size Pediatrics Rats Rats, Sprague-Dawley Science & Technology Urology & Nephrology
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