Comparison of Sympathetic Blocking Drugs in Prevention of Lethal Effects of Endotoxin.

Summary and conclusions The prophylactic and therapeutic effects of phenoxybenzamine, chlorpromazine, and phentolamine against the lethal effects of Escherichia coli endotoxin in mice were compared. Mortality was observed at 24 hours and 7 days to clarify the value of these agents for “long-term” pr...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1964-03, Vol.115 (3), p.627-630
Hauptverfasser:	Weil, Max H., Allen, Kenneth S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chlorpromazine Endotoxins Escherichia coli Infections Mice Pharmacology Phenoxybenzamine Phentolamine Toxicology
Online-Zugang:	Volltext
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