Phase 2 study with Baker's Antifol in solid tumors

One hundred thirty-eight adults with advanced cancers were treated with Baker's Antifol. The complete response + partial response rate was only 10%. Best responses were obtained in 31 patients with lung adenocarcinoma (complete response + partial response, 13%), in 25 patients with colorectal c...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1977-04, Vol.37 (4), p.980
Hauptverfasser:	Rodriguez, V, Richman, S P, Benjamin, R S, Burgess, M A, Murphy, W K, Valdivieso, M, Banner, R L, Gutterman, J U, Bodey, G P, Freireich, E J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adolescent Adult Aged Carcinoma, Squamous Cell - drug therapy Colonic Neoplasms - drug therapy Drug Eruptions - etiology Female Folic Acid Antagonists - administration & dosage Folic Acid Antagonists - adverse effects Folic Acid Antagonists - therapeutic use Head and Neck Neoplasms - drug therapy Humans Kidney Neoplasms - drug therapy Lung Neoplasms - drug therapy Male Melanoma - drug therapy Middle Aged Neoplasms - drug therapy Rectal Neoplasms - drug therapy Remission, Spontaneous Sarcoma - drug therapy Stomatitis - chemically induced Triazines - administration & dosage Triazines - therapeutic use
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