TCP pilus biosynthesis in Vibrio cholerae O1 : gene sequence of tcpC encoding an outer membrane lipoprotein
The nucleotide sequence of the tcpC gene has been determined. It encodes a 53995-Da protein precursor with a signal sequence and cleavage site typical of a number of outer membrane lipoproteins, which are cleaved by the equivalent of signal peptidase II (Lsp) of Escherichia coli. The location of the...
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| Veröffentlicht in: | FEMS microbiology letters 1992-10, Vol.97 (1-2), p.179-184 |
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| container_title | FEMS microbiology letters |
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| creator | OGIERMAN, M. A MANNING, P. A |
| description | The nucleotide sequence of the tcpC gene has been determined. It encodes a 53995-Da protein precursor with a signal sequence and cleavage site typical of a number of outer membrane lipoproteins, which are cleaved by the equivalent of signal peptidase II (Lsp) of Escherichia coli. The location of the tcpC gene is such that it is predicted to be translationally coupled to the 5' and 3' flanking genes, tcpY and tcpD, respectively, indicating that it forms part of an operon. Together with the lipoprotein signal sequence and the several hydrophobic domains it seems likely that TcpC is a surface-anchored trans-outer membrane lipoprotein. |
| doi_str_mv | 10.1016/0378-1097(92)90383-Y |
| format | Article |
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Together with the lipoprotein signal sequence and the several hydrophobic domains it seems likely that TcpC is a surface-anchored trans-outer membrane lipoprotein.</description><identifier>ISSN: 0378-1097</identifier><identifier>EISSN: 1574-6968</identifier><identifier>DOI: 10.1016/0378-1097(92)90383-Y</identifier><identifier>PMID: 1358749</identifier><identifier>CODEN: FMLED7</identifier><language>eng</language><publisher>Oxford: Blackwell</publisher><subject>Amino Acid Sequence ; Bacterial Outer Membrane Proteins - biosynthesis ; Bacterial Outer Membrane Proteins - genetics ; Bacterial Toxins - biosynthesis ; Bacterial Toxins - genetics ; Base Sequence ; Biological and medical sciences ; DNA, Bacterial - genetics ; Fimbriae, Bacterial - metabolism ; Fundamental and applied biological sciences. Psychology ; Genes, Bacterial ; Lipoproteins - biosynthesis ; Lipoproteins - genetics ; Microbiology ; Molecular Sequence Data ; Morphology, structure, chemical composition, physicochemical properties ; Sequence Homology, Amino Acid ; Vibrio cholerae - genetics ; Vibrio cholerae - metabolism ; Virology</subject><ispartof>FEMS microbiology letters, 1992-10, Vol.97 (1-2), p.179-184</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4322224$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1358749$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>OGIERMAN, M. A</creatorcontrib><creatorcontrib>MANNING, P. A</creatorcontrib><title>TCP pilus biosynthesis in Vibrio cholerae O1 : gene sequence of tcpC encoding an outer membrane lipoprotein</title><title>FEMS microbiology letters</title><addtitle>FEMS Microbiol Lett</addtitle><description>The nucleotide sequence of the tcpC gene has been determined. It encodes a 53995-Da protein precursor with a signal sequence and cleavage site typical of a number of outer membrane lipoproteins, which are cleaved by the equivalent of signal peptidase II (Lsp) of Escherichia coli. The location of the tcpC gene is such that it is predicted to be translationally coupled to the 5' and 3' flanking genes, tcpY and tcpD, respectively, indicating that it forms part of an operon. Together with the lipoprotein signal sequence and the several hydrophobic domains it seems likely that TcpC is a surface-anchored trans-outer membrane lipoprotein.</description><subject>Amino Acid Sequence</subject><subject>Bacterial Outer Membrane Proteins - biosynthesis</subject><subject>Bacterial Outer Membrane Proteins - genetics</subject><subject>Bacterial Toxins - biosynthesis</subject><subject>Bacterial Toxins - genetics</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>DNA, Bacterial - genetics</subject><subject>Fimbriae, Bacterial - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes, Bacterial</subject><subject>Lipoproteins - biosynthesis</subject><subject>Lipoproteins - genetics</subject><subject>Microbiology</subject><subject>Molecular Sequence Data</subject><subject>Morphology, structure, chemical composition, physicochemical properties</subject><subject>Sequence Homology, Amino Acid</subject><subject>Vibrio cholerae - genetics</subject><subject>Vibrio cholerae - metabolism</subject><subject>Virology</subject><issn>0378-1097</issn><issn>1574-6968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9LxDAQxYMo67r6DRRyENFDNWmyTeJNiv9gYT2sgqeSpNPdaNvUpj3stzdgcS7D8H68eTMInVNySwnN7ggTMqFEiWuV3ijCJEs-D9CcLgVPMpXJQzT_R47RSQhfhBCekmyGZpQtpeBqjr43-RvuXD0GbJwP-3bYQXABuxZ_ONM7j-3O19BrwGuK7_EWWsABfkZoLWBf4cF2OY6DL127xbrFfhygxw00pteRrV3nu94P4NpTdFTpOsDZ1Bfo_elxk78kq_Xza_6wSjqaiSGRklNtjRBgy0ouqZWcMUkkFak2aVpxRUiZEVGVWpmKczDWpktNoYwskYYt0NWfb9wbg4ahaFywUNcxjx9DIViqKI2uC3QxgaNpoCy63jW63xfTd6J-Oek6WF1X8SDrwj_GWRqLs1_tH3TH</recordid><startdate>19921001</startdate><enddate>19921001</enddate><creator>OGIERMAN, M. A</creator><creator>MANNING, P. A</creator><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19921001</creationdate><title>TCP pilus biosynthesis in Vibrio cholerae O1 : gene sequence of tcpC encoding an outer membrane lipoprotein</title><author>OGIERMAN, M. A ; MANNING, P. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p167t-8841acb77ecdf851c8433808172ab22f4900d607fda9bf44ebcc25a1ed51c08b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Amino Acid Sequence</topic><topic>Bacterial Outer Membrane Proteins - biosynthesis</topic><topic>Bacterial Outer Membrane Proteins - genetics</topic><topic>Bacterial Toxins - biosynthesis</topic><topic>Bacterial Toxins - genetics</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>DNA, Bacterial - genetics</topic><topic>Fimbriae, Bacterial - metabolism</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes, Bacterial</topic><topic>Lipoproteins - biosynthesis</topic><topic>Lipoproteins - genetics</topic><topic>Microbiology</topic><topic>Molecular Sequence Data</topic><topic>Morphology, structure, chemical composition, physicochemical properties</topic><topic>Sequence Homology, Amino Acid</topic><topic>Vibrio cholerae - genetics</topic><topic>Vibrio cholerae - metabolism</topic><topic>Virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>OGIERMAN, M. A</creatorcontrib><creatorcontrib>MANNING, P. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>FEMS microbiology letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>OGIERMAN, M. A</au><au>MANNING, P. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>TCP pilus biosynthesis in Vibrio cholerae O1 : gene sequence of tcpC encoding an outer membrane lipoprotein</atitle><jtitle>FEMS microbiology letters</jtitle><addtitle>FEMS Microbiol Lett</addtitle><date>1992-10-01</date><risdate>1992</risdate><volume>97</volume><issue>1-2</issue><spage>179</spage><epage>184</epage><pages>179-184</pages><issn>0378-1097</issn><eissn>1574-6968</eissn><coden>FMLED7</coden><abstract>The nucleotide sequence of the tcpC gene has been determined. It encodes a 53995-Da protein precursor with a signal sequence and cleavage site typical of a number of outer membrane lipoproteins, which are cleaved by the equivalent of signal peptidase II (Lsp) of Escherichia coli. The location of the tcpC gene is such that it is predicted to be translationally coupled to the 5' and 3' flanking genes, tcpY and tcpD, respectively, indicating that it forms part of an operon. Together with the lipoprotein signal sequence and the several hydrophobic domains it seems likely that TcpC is a surface-anchored trans-outer membrane lipoprotein.</abstract><cop>Oxford</cop><pub>Blackwell</pub><pmid>1358749</pmid><doi>10.1016/0378-1097(92)90383-Y</doi><tpages>6</tpages></addata></record> |
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| ispartof | FEMS microbiology letters, 1992-10, Vol.97 (1-2), p.179-184 |
| issn | 0378-1097 1574-6968 |
| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection; Oxford University Press Journals Digital Archive Legacy |
| subjects | Amino Acid Sequence Bacterial Outer Membrane Proteins - biosynthesis Bacterial Outer Membrane Proteins - genetics Bacterial Toxins - biosynthesis Bacterial Toxins - genetics Base Sequence Biological and medical sciences DNA, Bacterial - genetics Fimbriae, Bacterial - metabolism Fundamental and applied biological sciences. Psychology Genes, Bacterial Lipoproteins - biosynthesis Lipoproteins - genetics Microbiology Molecular Sequence Data Morphology, structure, chemical composition, physicochemical properties Sequence Homology, Amino Acid Vibrio cholerae - genetics Vibrio cholerae - metabolism Virology |
| title | TCP pilus biosynthesis in Vibrio cholerae O1 : gene sequence of tcpC encoding an outer membrane lipoprotein |
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