Posttreatment itraconazole levels in the nail. New implications for treatment in onychomycosis

A problem in the treatment of onychomycosis is the lengthy duration of therapy. The pharmacokinetics of itraconazole suggest a potential for briefer treatment. This study was designed to investigate itraconazole nail kinetics in 39 patients with onychomycosis in relation to their therapeutic outcome...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 1992-05, Vol.26 (5 Pt 1), p.731
Hauptverfasser:	Willemsen, M, De Doncker, P, Willems, J, Woestenborghs, R, Van de Velde, V, Heykants, J, Van Cutsem, J, Cauwenbergh, G, Roseeuw, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - administration & dosage Antifungal Agents - adverse effects Antifungal Agents - analysis Antifungal Agents - pharmacokinetics Capsules Chromatography, High Pressure Liquid Drug Evaluation Female Fingers Humans Itraconazole Ketoconazole - administration & dosage Ketoconazole - adverse effects Ketoconazole - analogs & derivatives Ketoconazole - analysis Ketoconazole - pharmacokinetics Male Nails - chemistry Nails - metabolism Onychomycosis - drug therapy Onychomycosis - metabolism Remission Induction Time Factors Toes
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