Evidence for Cytokine Dysregulation in Multiple Sclerosis: Peripheral Blood Mononuclear Cell Production of Pro-inflammatory and Anti-inflammatory Cytokines During Relapse and Remission

We investigated circulating anti-inflammatory and pro-inflammatory cytokines, and their ex vivo PBMC production in the absence or presence of the neuroantigens myelin basic protein (MBP) and myelin oligodendrocyte glycoprotein (MOG) and T cell mitogen (PHA) in MS patients in relapse and remission, p...

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Veröffentlicht in:	Autoimmunity (Chur, Switzerland) Switzerland), 2003-05, Vol.36 (3), p.133-141
Hauptverfasser:	Hollifield, Robert D., Harbige, Laurence S., Pham-Dinh, Danielle, Sharief, Mohammed K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Biologically active TGF-β1 Cytokines Cytokines - blood Cytokines - metabolism Female Humans Interferon-gamma - metabolism Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Male MBP Medical sciences Middle Aged MOG Multiple sclerosis Multiple Sclerosis - metabolism Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Myelin Proteins Myelin-Associated Glycoprotein - pharmacology Myelin-Oligodendrocyte Glycoprotein Neurology Relapse and remission Transforming Growth Factor beta - metabolism
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