Blood Markers for Vasculogenesis Increase with Tumor Progression in Patients with Breast Carcinoma

Recent studies show that AC133-a hematopoietic stem cell antigen, when coex-pressed with endothelial markers, identifies a population of endothelial precursor cells (EPCs) in peripheral blood that function in tumor vasculogenesis in animals. Little is known about whether EPCs contribute to human tum...

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Veröffentlicht in:	Cancer biology & therapy 2003-05, Vol.2 (3), p.255-256
Hauptverfasser:	Sussman, Louis K., Upalakalin, Jan Nalinee, Roberts, Mark J., Kocher, Olivier, Benjamin, Laura E.
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Antigens, CD Binding Biology Biomarkers, Tumor - genetics Bioscience Breast Neoplasms - blood supply Calcium Cancer Carcinoma, Ductal, Breast - blood supply Carcinoma, Intraductal, Noninfiltrating - blood supply Cell Cycle Disease Progression DNA Primers - chemistry Endothelium, Vascular - metabolism Female Gene Expression Regulation, Neoplastic Glycoproteins - genetics Humans Landes Neoplasm Proteins - genetics Neovascularization, Pathologic - blood Organogenesis Peptides - genetics Proteins Receptor, TIE-2 - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Vascular Endothelial Growth Factor Receptor-2 - genetics
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