Prevalence of infection by HIV and hepatitis C virus in a cohort of patients on methadone treatment
Methadone maintenance treatment reduces drug-related-harm. The aims of the study were: a) to analyze the temporal tendencies of prevalence of infection by HIV and hepatitis C virus, and b) to evaluate if the adherence to methadone maintenance treatment protects against the infection by HIV and hepat...
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| Veröffentlicht in: | Medicina clínica 2003-05, Vol.120 (20), p.765 |
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| container_title | Medicina clínica |
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| creator | Esteban, Javier Gimeno, Carmen Aragonés, Amparo Barril, José Pellín, María de la Cruz |
| description | Methadone maintenance treatment reduces drug-related-harm. The aims of the study were: a) to analyze the temporal tendencies of prevalence of infection by HIV and hepatitis C virus, and b) to evaluate if the adherence to methadone maintenance treatment protects against the infection by HIV and hepatitis C virus.
Retrospective longitudinal study with All the 1,487 patients receiving treatment in the Province of Alicante between June 1990 and December 1997. The prevalence of infection by HIV and hepatitis C virus were computed. The variables associated to the infection by HIV and hepatitis C virus were recognized though a model of logistic regression.
The prevalence of infection by HIV decreased, and the prevalence of infection by hepatitis C virus increased along the studied period. The independent predictors with regard to the infection by HIV were the age of beginning in treatment (odds ratio [OR] = 0.95; 95% confident interval [95%CI], 0.93-0.97; p < 0.001), total time within treatment (OR = 0.99; 95%CI, 0.98-1.0; p = 0.01) and non-parenteral route of administration (OR = 0.25; 95%CI, 0.18-0.33; p < 0.001).
To be admitted to methadone maintenance treatment for the first time after opiate dependence has been developed and to remain in treatment for long periods of time, all that decreases the risk of infection by HIV. |
| doi_str_mv | 10.1157/13048329 |
| format | Article |
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Retrospective longitudinal study with All the 1,487 patients receiving treatment in the Province of Alicante between June 1990 and December 1997. The prevalence of infection by HIV and hepatitis C virus were computed. The variables associated to the infection by HIV and hepatitis C virus were recognized though a model of logistic regression.
The prevalence of infection by HIV decreased, and the prevalence of infection by hepatitis C virus increased along the studied period. The independent predictors with regard to the infection by HIV were the age of beginning in treatment (odds ratio [OR] = 0.95; 95% confident interval [95%CI], 0.93-0.97; p < 0.001), total time within treatment (OR = 0.99; 95%CI, 0.98-1.0; p = 0.01) and non-parenteral route of administration (OR = 0.25; 95%CI, 0.18-0.33; p < 0.001).
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Retrospective longitudinal study with All the 1,487 patients receiving treatment in the Province of Alicante between June 1990 and December 1997. The prevalence of infection by HIV and hepatitis C virus were computed. The variables associated to the infection by HIV and hepatitis C virus were recognized though a model of logistic regression.
The prevalence of infection by HIV decreased, and the prevalence of infection by hepatitis C virus increased along the studied period. The independent predictors with regard to the infection by HIV were the age of beginning in treatment (odds ratio [OR] = 0.95; 95% confident interval [95%CI], 0.93-0.97; p < 0.001), total time within treatment (OR = 0.99; 95%CI, 0.98-1.0; p = 0.01) and non-parenteral route of administration (OR = 0.25; 95%CI, 0.18-0.33; p < 0.001).
To be admitted to methadone maintenance treatment for the first time after opiate dependence has been developed and to remain in treatment for long periods of time, all that decreases the risk of infection by HIV.</description><subject>Adult</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Hepatitis C - complications</subject><subject>Hepatitis C - epidemiology</subject><subject>Hepatitis C - virology</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - virology</subject><subject>Humans</subject><subject>Male</subject><subject>Methadone - therapeutic use</subject><subject>Odds Ratio</subject><subject>Opioid-Related Disorders - rehabilitation</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Spain - epidemiology</subject><issn>0025-7753</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1T8tKAzEUzUKxtQp-geQHRvOauclSBrWFgi7UbcnkwUQ6mSFJC_17p6ibe7nncTkHoTtKHiit4ZFyIiRn6gItCWF1BVDzBbrO-ft8cgpXaEEZKFAMlsi8J3fUexeNw6PHIXpnShgj7k54vfnCOlrcu0mXUELGLT6GdMizDGtsxn5M5ew60y6WjGff4Eqv7RgdLsnpMsz4Dbr0ep_d7d9eoc-X5492XW3fXjft07YyFGSpvKdCC2sacHNQILTxWtFGzVN1QloqjDFzG8-lJZ552VhFuGRMgPYCPF-h-9-_06EbnN1NKQw6nXb_bfkPfs5TuQ</recordid><startdate>20030531</startdate><enddate>20030531</enddate><creator>Esteban, Javier</creator><creator>Gimeno, Carmen</creator><creator>Aragonés, Amparo</creator><creator>Barril, José</creator><creator>Pellín, María de la Cruz</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20030531</creationdate><title>Prevalence of infection by HIV and hepatitis C virus in a cohort of patients on methadone treatment</title><author>Esteban, Javier ; Gimeno, Carmen ; Aragonés, Amparo ; Barril, José ; Pellín, María de la Cruz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c178t-ff14a4dc67e0257016fa9169fa99b48d14ccc775f38d0f2f86d90382247af47f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Hepatitis C - complications</topic><topic>Hepatitis C - epidemiology</topic><topic>Hepatitis C - virology</topic><topic>HIV Infections - complications</topic><topic>HIV Infections - epidemiology</topic><topic>HIV Infections - virology</topic><topic>Humans</topic><topic>Male</topic><topic>Methadone - therapeutic use</topic><topic>Odds Ratio</topic><topic>Opioid-Related Disorders - rehabilitation</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Spain - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Esteban, Javier</creatorcontrib><creatorcontrib>Gimeno, Carmen</creatorcontrib><creatorcontrib>Aragonés, Amparo</creatorcontrib><creatorcontrib>Barril, José</creatorcontrib><creatorcontrib>Pellín, María de la Cruz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Medicina clínica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Esteban, Javier</au><au>Gimeno, Carmen</au><au>Aragonés, Amparo</au><au>Barril, José</au><au>Pellín, María de la Cruz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of infection by HIV and hepatitis C virus in a cohort of patients on methadone treatment</atitle><jtitle>Medicina clínica</jtitle><addtitle>Med Clin (Barc)</addtitle><date>2003-05-31</date><risdate>2003</risdate><volume>120</volume><issue>20</issue><spage>765</spage><pages>765-</pages><issn>0025-7753</issn><abstract>Methadone maintenance treatment reduces drug-related-harm. The aims of the study were: a) to analyze the temporal tendencies of prevalence of infection by HIV and hepatitis C virus, and b) to evaluate if the adherence to methadone maintenance treatment protects against the infection by HIV and hepatitis C virus.
Retrospective longitudinal study with All the 1,487 patients receiving treatment in the Province of Alicante between June 1990 and December 1997. The prevalence of infection by HIV and hepatitis C virus were computed. The variables associated to the infection by HIV and hepatitis C virus were recognized though a model of logistic regression.
The prevalence of infection by HIV decreased, and the prevalence of infection by hepatitis C virus increased along the studied period. The independent predictors with regard to the infection by HIV were the age of beginning in treatment (odds ratio [OR] = 0.95; 95% confident interval [95%CI], 0.93-0.97; p < 0.001), total time within treatment (OR = 0.99; 95%CI, 0.98-1.0; p = 0.01) and non-parenteral route of administration (OR = 0.25; 95%CI, 0.18-0.33; p < 0.001).
To be admitted to methadone maintenance treatment for the first time after opiate dependence has been developed and to remain in treatment for long periods of time, all that decreases the risk of infection by HIV.</abstract><cop>Spain</cop><pmid>12797927</pmid><doi>10.1157/13048329</doi></addata></record> |
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| ispartof | Medicina clínica, 2003-05, Vol.120 (20), p.765 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Analgesics, Opioid - therapeutic use Cohort Studies Female Hepatitis C - complications Hepatitis C - epidemiology Hepatitis C - virology HIV Infections - complications HIV Infections - epidemiology HIV Infections - virology Humans Male Methadone - therapeutic use Odds Ratio Opioid-Related Disorders - rehabilitation Prevalence Retrospective Studies Risk Factors Spain - epidemiology |
| title | Prevalence of infection by HIV and hepatitis C virus in a cohort of patients on methadone treatment |
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