Prior exposure to Mannheimia haemolytica leukotoxin or LPS enhances beta(2)-integrin expression by bovine neutrophils and augments LKT cytotoxicity

Mannheimia (Pasteurella) haemolytica serotype1 produces a variety of virulence factors that play an important role during the pathogenesis of bovine pneumonic pasteurellosis. Among these, a leukotoxin (LKT) and lipopolysaccharide (LPS) are thought to be the primary virulence factors that contribute...

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Veröffentlicht in:	Microbial pathogenesis 2003-06, Vol.34 (6), p.267
Hauptverfasser:	Leite, F, Gyles, S, Atapattu, D, Maheswaran, S K, Czuprynski, C J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Apoptosis Bacterial Toxins - toxicity Binding Sites Blotting, Western - methods Cattle CD18 Antigens - biosynthesis CD18 Antigens - metabolism Cytotoxins - toxicity Exotoxins - toxicity Lipopolysaccharides - toxicity Lymphocyte Function-Associated Antigen-1 - analysis Mannheimia haemolytica - pathogenicity Mutation Neutrophils - drug effects Neutrophils - metabolism
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