Primary ALK Positive Anaplastic Large Cell Lymphoma of the Pancreas
Here we present an unusual case of anaplastic lymphoma kinase positive anaplastic large cell lymphoma (ALCL), appearing as a primary tumor of the pancreas which invaded into the adjacent duodenal wall, causing upper gastrointestinal bleeding. After complete resection of the tumor (Whipple's ope...
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| Veröffentlicht in: | Leukemia & lymphoma 2003, Vol.44 (1), p.205-207 |
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| container_title | Leukemia & lymphoma |
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| creator | Cohen, Yossi Libster, Diana Amir, Gail Hiller, Nurith Da'as, Nael Yehuda, Dina Ben Polliack, Aaron |
| description | Here we present an unusual case of anaplastic lymphoma kinase positive anaplastic large cell lymphoma (ALCL), appearing as a primary tumor of the pancreas which invaded into the adjacent duodenal wall, causing upper gastrointestinal bleeding. After complete resection of the tumor (Whipple's operation), the patient received 4 cycles of CHOP chemotherapy. Currently, 2 years after diagnosis the patient still remains lymphoma free. Primary ALCL of the pancreas is very rare and has only been reported on one previous occasion. Nevertheless, lymphoma should be considered in the differential diagnosis of pancreatic tumors and an attempt to obtain tissue diagnosis is always necessary before continuing with radical surgery, especially in young patients. |
| doi_str_mv | 10.1080/1042819021000054715 |
| format | Article |
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Nevertheless, lymphoma should be considered in the differential diagnosis of pancreatic tumors and an attempt to obtain tissue diagnosis is always necessary before continuing with radical surgery, especially in young patients.</description><subject>Adult</subject><subject>Alk Positive Lymphoma</subject><subject>Anaplastic Large Cell Lymphoma</subject><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Duodenal Neoplasms - etiology</subject><subject>Duodenal Neoplasms - therapy</subject><subject>Humans</subject><subject>Immunophenotyping</subject><subject>Ki-1</subject><subject>Lymphoma, Large-Cell, Anaplastic - diagnosis</subject><subject>Lymphoma, Large-Cell, Anaplastic - pathology</subject><subject>Lymphoma, Large-Cell, Anaplastic - therapy</subject><subject>Male</subject><subject>Necrosis</subject><subject>Neoplasm Invasiveness - pathology</subject><subject>Pancreas</subject><subject>Pancreatic Neoplasms - diagnosis</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Pancreatic Neoplasms - therapy</subject><subject>Remission Induction - methods</subject><issn>1042-8194</issn><issn>1029-2403</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFqGzEQhkVJaZy0TxAIOuW2qUarXVmHFoxpk5KF-JCexVgZ1Rt2V660TvDbV8aGECiOLtLhm1__fIxdgLgGMRVfQSg5BSMkiHwqpaH6wCYgpCmkEuXJ7q1kkRF1ys5SetpRppaf2CnI2gDU9YTNF7HtMW75rLnji5DasX0mPhtw3WEaW8cbjH-Iz6nreLPt16vQIw-ejyviCxxcJEyf2UePXaIvh_uc_f7542F-WzT3N7_ms6ZwSsFYIC1FSQBO-9wfAb1SvvZKOzWtnKwVVTStNJa4JCOJhMEShBHaeOfymuU5u9rnrmP4u6E02r5NLjfDgcImWV1mG1Wt3wXBGF2BrjJY7kEXQ0qRvF3vdVgQdifZ_kdynro8xG-WPT2-zhysZuD7HmgHH2KPLyF2j3bEbReij9lam2x5_IdvbwJWhN24chjJPoVNHLLlow3_AVSCm00</recordid><startdate>2003</startdate><enddate>2003</enddate><creator>Cohen, Yossi</creator><creator>Libster, Diana</creator><creator>Amir, Gail</creator><creator>Hiller, Nurith</creator><creator>Da'as, Nael</creator><creator>Yehuda, Dina Ben</creator><creator>Polliack, Aaron</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>2003</creationdate><title>Primary ALK Positive Anaplastic Large Cell Lymphoma of the Pancreas</title><author>Cohen, Yossi ; 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After complete resection of the tumor (Whipple's operation), the patient received 4 cycles of CHOP chemotherapy. Currently, 2 years after diagnosis the patient still remains lymphoma free. Primary ALCL of the pancreas is very rare and has only been reported on one previous occasion. Nevertheless, lymphoma should be considered in the differential diagnosis of pancreatic tumors and an attempt to obtain tissue diagnosis is always necessary before continuing with radical surgery, especially in young patients.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>12691166</pmid><doi>10.1080/1042819021000054715</doi><tpages>3</tpages></addata></record> |
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| ispartof | Leukemia & lymphoma, 2003, Vol.44 (1), p.205-207 |
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| subjects | Adult Alk Positive Lymphoma Anaplastic Large Cell Lymphoma Antineoplastic Combined Chemotherapy Protocols - therapeutic use Duodenal Neoplasms - etiology Duodenal Neoplasms - therapy Humans Immunophenotyping Ki-1 Lymphoma, Large-Cell, Anaplastic - diagnosis Lymphoma, Large-Cell, Anaplastic - pathology Lymphoma, Large-Cell, Anaplastic - therapy Male Necrosis Neoplasm Invasiveness - pathology Pancreas Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Remission Induction - methods |
| title | Primary ALK Positive Anaplastic Large Cell Lymphoma of the Pancreas |
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