Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4

Fibroblast growth factor receptors (FGFRs) have been implicated in a multitude of proliferative functions, and FGFR4 is expressed differentially in normal and neoplastic pituitary. Human pituitary tumors express a truncated FGFR4 isoform (ptd-FGFR4) for which transcription is initiated from a downst...

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Veröffentlicht in:	The Journal of biological chemistry 2003-05, Vol.278 (22), p.19597
Hauptverfasser:	Yu, ShunJiang, Asa, Sylvia L, Weigel, Ronald J, Ezzat, Shereen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Cell Line DNA Primers DNA-Binding Proteins - metabolism Humans Introns Mutagenesis, Site-Directed Pituitary Neoplasms - metabolism Pituitary Neoplasms - pathology Promoter Regions, Genetic Rats Receptor, Fibroblast Growth Factor, Type 4 Receptors, Fibroblast Growth Factor - genetics Transcription Factor AP-2 Transcription Factors - metabolism
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