Efficiency of Dispatch and Infiltrator Cardiac Infusion Catheters in Arterial Localization of Nanoparticles in a Porcine Coronary Model of Restenosis

Localized intramural delivery of sustained release biodegradable nanoparticles containing an antiproliferative agent could provide prolonged drug effect at the site of vascular injury that could inhibit the proliferation of smooth muscle cells and hence restenosis. The efficiency of arterial localiz...

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Veröffentlicht in:	Journal of drug targeting 2002-09, Vol.10 (6), p.515-523
Hauptverfasser:	Panyam, J., Lof, J., O'Leary, E., Labhasetwar, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Coronary Restenosis - drug therapy Disease Models, Animal General pharmacology Infusions, Intra-Arterial - instrumentation Infusions, Intra-Arterial - methods Local Delivery Medical sciences Microspheres Nanotechnology - methods Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Restenosis Site-specific Therapy Sustained Release Swine
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