A case of primary non-Hodgkin lymphoma of the lacrimal sac

Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervic...

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Veröffentlicht in:Journal français d'ophtalmologie 2002-11, Vol.25 (9), p.931
Hauptverfasser: Buc, D, Travade, P, Kemeny, J L, Bacin, F
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creator Buc, D
Travade, P
Kemeny, J L
Bacin, F
description Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervical nodes. Pathological studies of the mass revealed diffuse malignant lymphoma with large B cells. The lymphoma was classified as stage IIE using Ann Arbor staging after clinical, biological and radiological examination. Six CHOP systemic chemotherapy were proposed. After 12 months and only 4 cures because of hematological complications and cardiac toxicity, the patient was disease-free. Primary non-Hodgkin lymphoma of the lacrimal sac is extremely rare. Collaboration between the ophthalmologist, anatomopathologist and oncologist allowed us to determine the type and the extension and to propose an aggressive but successful treatment in this highly malignant and very localized lymphoma.
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subjects Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biopsy
Combined Modality Therapy
Cyclophosphamide - therapeutic use
Dacryocystorhinostomy
Disease-Free Survival
Doxorubicin - therapeutic use
Eye Neoplasms - diagnosis
Eye Neoplasms - drug therapy
Eye Neoplasms - pathology
Eye Neoplasms - surgery
Female
Follow-Up Studies
Humans
Lymphoma, B-Cell - diagnosis
Lymphoma, B-Cell - drug therapy
Lymphoma, B-Cell - pathology
Lymphoma, B-Cell - surgery
Nasolacrimal Duct - pathology
Prednisone - therapeutic use
Time Factors
Tomography, X-Ray Computed
Vincristine - therapeutic use
title A case of primary non-Hodgkin lymphoma of the lacrimal sac
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