A case of primary non-Hodgkin lymphoma of the lacrimal sac
Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervic...
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Veröffentlicht in: | Journal français d'ophtalmologie 2002-11, Vol.25 (9), p.931 |
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description | Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervical nodes. Pathological studies of the mass revealed diffuse malignant lymphoma with large B cells. The lymphoma was classified as stage IIE using Ann Arbor staging after clinical, biological and radiological examination. Six CHOP systemic chemotherapy were proposed. After 12 months and only 4 cures because of hematological complications and cardiac toxicity, the patient was disease-free. Primary non-Hodgkin lymphoma of the lacrimal sac is extremely rare. Collaboration between the ophthalmologist, anatomopathologist and oncologist allowed us to determine the type and the extension and to propose an aggressive but successful treatment in this highly malignant and very localized lymphoma. |
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We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervical nodes. Pathological studies of the mass revealed diffuse malignant lymphoma with large B cells. The lymphoma was classified as stage IIE using Ann Arbor staging after clinical, biological and radiological examination. Six CHOP systemic chemotherapy were proposed. After 12 months and only 4 cures because of hematological complications and cardiac toxicity, the patient was disease-free. Primary non-Hodgkin lymphoma of the lacrimal sac is extremely rare. Collaboration between the ophthalmologist, anatomopathologist and oncologist allowed us to determine the type and the extension and to propose an aggressive but successful treatment in this highly malignant and very localized lymphoma.</description><identifier>ISSN: 0181-5512</identifier><identifier>PMID: 12515939</identifier><language>fre</language><publisher>France</publisher><subject>Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Biopsy ; Combined Modality Therapy ; Cyclophosphamide - therapeutic use ; Dacryocystorhinostomy ; Disease-Free Survival ; Doxorubicin - therapeutic use ; Eye Neoplasms - diagnosis ; Eye Neoplasms - drug therapy ; Eye Neoplasms - pathology ; Eye Neoplasms - surgery ; Female ; Follow-Up Studies ; Humans ; Lymphoma, B-Cell - diagnosis ; Lymphoma, B-Cell - drug therapy ; Lymphoma, B-Cell - pathology ; Lymphoma, B-Cell - surgery ; Nasolacrimal Duct - pathology ; Prednisone - therapeutic use ; Time Factors ; Tomography, X-Ray Computed ; Vincristine - therapeutic use</subject><ispartof>Journal français d'ophtalmologie, 2002-11, Vol.25 (9), p.931</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12515939$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Buc, D</creatorcontrib><creatorcontrib>Travade, P</creatorcontrib><creatorcontrib>Kemeny, J L</creatorcontrib><creatorcontrib>Bacin, F</creatorcontrib><title>A case of primary non-Hodgkin lymphoma of the lacrimal sac</title><title>Journal français d'ophtalmologie</title><addtitle>J Fr Ophtalmol</addtitle><description>Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. We report the case of an 80-year-old woman presenting with epiphora and swelling of the left lacrimal area. A dacryocystorhinostomy was programmed, but within few weeks a painful tumor appeared with cervical nodes. Pathological studies of the mass revealed diffuse malignant lymphoma with large B cells. The lymphoma was classified as stage IIE using Ann Arbor staging after clinical, biological and radiological examination. Six CHOP systemic chemotherapy were proposed. After 12 months and only 4 cures because of hematological complications and cardiac toxicity, the patient was disease-free. Primary non-Hodgkin lymphoma of the lacrimal sac is extremely rare. Collaboration between the ophthalmologist, anatomopathologist and oncologist allowed us to determine the type and the extension and to propose an aggressive but successful treatment in this highly malignant and very localized lymphoma.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Biopsy</subject><subject>Combined Modality Therapy</subject><subject>Cyclophosphamide - therapeutic use</subject><subject>Dacryocystorhinostomy</subject><subject>Disease-Free Survival</subject><subject>Doxorubicin - therapeutic use</subject><subject>Eye Neoplasms - diagnosis</subject><subject>Eye Neoplasms - drug therapy</subject><subject>Eye Neoplasms - pathology</subject><subject>Eye Neoplasms - surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lymphoma, B-Cell - diagnosis</subject><subject>Lymphoma, B-Cell - drug therapy</subject><subject>Lymphoma, B-Cell - pathology</subject><subject>Lymphoma, B-Cell - surgery</subject><subject>Nasolacrimal Duct - pathology</subject><subject>Prednisone - therapeutic use</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed</subject><subject>Vincristine - therapeutic use</subject><issn>0181-5512</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tOQjEURTuQyEN_gfQHmvS099yeOiNExYTEiY7JuX0Icl-hOODvDRFHe7BXdta-EzMNBAoRzFTMS_nWWluHeC-mYBDQWz8TTysZuCQ5ZDmeDh2fLrIferUZ4tfx0Mv20o37oeNrf94n2XK4Uq0sHB7EJHNb0uMtF-Lz5fljvVHb99e39WqrRrD-rLgmAqjRhoYoBg-sK8wUyBsy3oFxda4C6-xtci5G11BlLGcTa83YgF2I5d_u-NN0Ke5unrv_E_YXyKtArA</recordid><startdate>200211</startdate><enddate>200211</enddate><creator>Buc, D</creator><creator>Travade, P</creator><creator>Kemeny, J L</creator><creator>Bacin, F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200211</creationdate><title>A case of primary non-Hodgkin lymphoma of the lacrimal sac</title><author>Buc, D ; Travade, P ; Kemeny, J L ; Bacin, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p139t-a68811653cb88dc91a045f8c89282971276f4ca0f93e77dd7b8423af2d60a5b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2002</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Biopsy</topic><topic>Combined Modality Therapy</topic><topic>Cyclophosphamide - therapeutic use</topic><topic>Dacryocystorhinostomy</topic><topic>Disease-Free Survival</topic><topic>Doxorubicin - therapeutic use</topic><topic>Eye Neoplasms - diagnosis</topic><topic>Eye Neoplasms - drug therapy</topic><topic>Eye Neoplasms - pathology</topic><topic>Eye Neoplasms - surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lymphoma, B-Cell - diagnosis</topic><topic>Lymphoma, B-Cell - drug therapy</topic><topic>Lymphoma, B-Cell - pathology</topic><topic>Lymphoma, B-Cell - surgery</topic><topic>Nasolacrimal Duct - pathology</topic><topic>Prednisone - therapeutic use</topic><topic>Time Factors</topic><topic>Tomography, X-Ray Computed</topic><topic>Vincristine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Buc, D</creatorcontrib><creatorcontrib>Travade, P</creatorcontrib><creatorcontrib>Kemeny, J L</creatorcontrib><creatorcontrib>Bacin, F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Journal français d'ophtalmologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Buc, D</au><au>Travade, P</au><au>Kemeny, J L</au><au>Bacin, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of primary non-Hodgkin lymphoma of the lacrimal sac</atitle><jtitle>Journal français d'ophtalmologie</jtitle><addtitle>J Fr Ophtalmol</addtitle><date>2002-11</date><risdate>2002</risdate><volume>25</volume><issue>9</issue><spage>931</spage><pages>931-</pages><issn>0181-5512</issn><abstract>Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare. 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subjects | Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biopsy Combined Modality Therapy Cyclophosphamide - therapeutic use Dacryocystorhinostomy Disease-Free Survival Doxorubicin - therapeutic use Eye Neoplasms - diagnosis Eye Neoplasms - drug therapy Eye Neoplasms - pathology Eye Neoplasms - surgery Female Follow-Up Studies Humans Lymphoma, B-Cell - diagnosis Lymphoma, B-Cell - drug therapy Lymphoma, B-Cell - pathology Lymphoma, B-Cell - surgery Nasolacrimal Duct - pathology Prednisone - therapeutic use Time Factors Tomography, X-Ray Computed Vincristine - therapeutic use |
title | A case of primary non-Hodgkin lymphoma of the lacrimal sac |
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