PULMONARY EFFECTS OF ULTRAFINE AND FINE AMMONIUM SALTS AEROSOLS IN HEALTHY AND MONOCROTALINE-TREATED RATS FOLLOWING SHORT-TERM EXPOSURE

In the present study the effects of a 3-day inhalation exposure to model compounds for ambient particulate matter were investigated: ammonium bisulfate, ammonium ferrosulfate, and ammonium nitrate, all components of the secondary aerosol fraction of ambient particulate matter (PM), and carbon black...

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Veröffentlicht in:	Inhalation toxicology 2002-12, Vol.14 (12), p.1215-1229
Hauptverfasser:	Cassee, F. R., Arts, J. H. E., Fokkens, P. H. B., Spoor, S. M., Boere, A. J. F., Bree, L. van, Dormans, J. A. M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Aerosols Air Pollutants - toxicity ammonium bisulfate ammonium ferrosulfate ammonium nitrate Ammonium Sulfate - administration & dosage Ammonium Sulfate - toxicity Animals Bronchoalveolar Lavage Fluid - chemistry Bronchoalveolar Lavage Fluid - cytology Ferrous Compounds - administration & dosage Ferrous Compounds - toxicity Hypertension, Pulmonary - chemically induced Hypertension, Pulmonary - metabolism Hypertension, Pulmonary - pathology Lung - metabolism Lung - pathology Macrophages, Alveolar - drug effects Macrophages, Alveolar - metabolism Male Monocrotaline Nitrates - administration & dosage Nitrates - toxicity Particle Size Quaternary Ammonium Compounds - administration & dosage Quaternary Ammonium Compounds - toxicity Rats Rats, Sprague-Dawley
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