Nuclear factor-kappaB and TNF-alpha mediate gastric ulceration induced by phorbol myristate acetate

Phorbol esters induce inflammation in rodents by activating protein kinase C. We determined whether nuclear factor-kappaB (NF-kappaB) and tumor necrosis factor-alpha (TNF-alpha) play role in the formation of gastric ulcer induced by phorbol-12-myristate-13-alphacetate (PMA) in rats. Subserosally inj...

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Veröffentlicht in:	Digestive diseases and sciences 2002-09, Vol.47 (9), p.2070
Hauptverfasser:	Takeuchi, Tetsu, Miura, Soichiro, Wang, Lin, Uehara, Keita, Mizumori, Misa, Kishikawa, Hiroshi, Hokari, Ryota, Higuchi, Hajime, Adachi, Masayuki, Nakamizo, Hiromasa, Ishii, Hiromasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gastric Mucosa - drug effects Male NF-kappa B - physiology Rats Rats, Wistar Stomach Ulcer - chemically induced Tetradecanoylphorbol Acetate Tumor Necrosis Factor-alpha - physiology
Online-Zugang:	Volltext
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