The cycad neurotoxic amino acid, β-N-methylamino-l-alanine (BMAA), elevates intracellular calcium levels in dissociated rat brain cells

Seeds of the Guam cycad Cycas micronesica K.D. Hill (Cycadaceae), which contain ss-methylamino-L-alanine (BMAA), have been implicated in the etiology of the devastating neurodisease ALS-PDC that is found among the native Chamorros on Guam. The disease also occurs in the native populations on Irian J...

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Veröffentlicht in:Journal of ethnopharmacology 2002-10, Vol.82 (2-3), p.159-167
Hauptverfasser: BROWNSON, Delia M, MABRY, Tom J, LESLIE, Steven W
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Sprache:eng
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