Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study
There has been a dramatic increase in the prevalence of antibiotic-resistant bacteria worldwide. In the Scandinavian countries at least 90% of total antibiotic use relates to outpatients and therefore it has become increasingly important to know the antibiotic prescription pattern of general practit...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of infectious diseases 2002, Vol.34 (8), p.602-609 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 609 |
|---|---|
| container_issue | 8 |
| container_start_page | 602 |
| container_title | Scandinavian journal of infectious diseases |
| container_volume | 34 |
| creator | Odenholt, Inga Bylander-Groth, Anita Frimodt-Möller, Niels Rokstad, Kirsten Skinlo Mölstad, Sigvard |
| description | There has been a dramatic increase in the prevalence of antibiotic-resistant bacteria worldwide. In the Scandinavian countries at least 90% of total antibiotic use relates to outpatients and therefore it has become increasingly important to know the antibiotic prescription pattern of general practitioners (GPs) in order to implement and monitor changes in antibiotic prescribing. The aim of the present study was to evaluate the prescription patterns of GPs in Denmark, Norway and Sweden. In order to achieve a reasonable comparison, a questionnaire consisting of 7 case reports concerning upper and lower respiratory tract infections, urinary tract infections and skin and soft tissue infections was sent to 1,000 GPs in the 3 countries. In general, the guidelines for the treatment of bacterial infections in the individual countries were followed by the responders. In all 3 countries, penicillin V was still the drug most frequently used in upper and lower respiratory tract infections. The greatest difference in prescribing patterns among the countries was seen in the treatment of urinary tract infections, recurrent pharyngeal tonsillitis, acute otitis media and acute exacerbation of chronic bronchitis. There were also differences in the dosing regimens, length of treatment and use of diagnostic techniques. |
| doi_str_mv | 10.1080/00365540210147624 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_12238578</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72103548</sourcerecordid><originalsourceid>FETCH-LOGICAL-c532t-888f792067e412f3f090d5198fa7e855c8f8ef7f0d339ef2478f3ed3f965a2f33</originalsourceid><addsrcrecordid>eNqFkUFv1DAQhS0EokvhB3BBucBtwY7txAEuS4GCtBJFhbM1ccbUVdZebIfV_nscdqFCSOUwsqz53tPMPEIeM_qcUUVfUMobKQWtGWWibWpxhyxYI9mSdYreJYu5vyyAOiEPUrqmlIqG0_vkhNU1V7JVCxLfOmsxojeYKuerlc-udyE7U11ETCaWn_9WXUDOGH2q3mDeIfrqHD1GGAsEJrvsQvn-Mrg04Afn4YeDl9Wq-jxhmrseXMTqMk_D_iG5Z2FM-Oj4npKv7999OfuwXH86_3i2Wi-N5HVeKqVs29W0aVGw2nJLOzrIspmFFpWURlmFtrV04LxDW4tWWY4Dt10jofD8lKwPvmmH26nX2-g2EPc6gNPjtC3Vl9IJdTmipF3Ta26U0mJoUPcorTZdD0b0jWoBi92zg902hu_zVnrjksFxBI9hSrotKfBy6_-CTDWsE3IG2QE0MaQU0f4ZkVE9B6z_CbhonhzNp36Dw43imGgBnh4BSAZGG8Ebl2443lFRTAv3-sA5b0PcwC7EcdAZ9mOIv0X8tjle_SW_QhjzlYGI-jpM0Zdgb9niJ0Rv02k</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>18619458</pqid></control><display><type>article</type><title>Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study</title><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><source>Taylor & Francis Journals Complete</source><creator>Odenholt, Inga ; Bylander-Groth, Anita ; Frimodt-Möller, Niels ; Rokstad, Kirsten Skinlo ; Mölstad, Sigvard</creator><creatorcontrib>Odenholt, Inga ; Bylander-Groth, Anita ; Frimodt-Möller, Niels ; Rokstad, Kirsten Skinlo ; Mölstad, Sigvard</creatorcontrib><description>There has been a dramatic increase in the prevalence of antibiotic-resistant bacteria worldwide. In the Scandinavian countries at least 90% of total antibiotic use relates to outpatients and therefore it has become increasingly important to know the antibiotic prescription pattern of general practitioners (GPs) in order to implement and monitor changes in antibiotic prescribing. The aim of the present study was to evaluate the prescription patterns of GPs in Denmark, Norway and Sweden. In order to achieve a reasonable comparison, a questionnaire consisting of 7 case reports concerning upper and lower respiratory tract infections, urinary tract infections and skin and soft tissue infections was sent to 1,000 GPs in the 3 countries. In general, the guidelines for the treatment of bacterial infections in the individual countries were followed by the responders. In all 3 countries, penicillin V was still the drug most frequently used in upper and lower respiratory tract infections. The greatest difference in prescribing patterns among the countries was seen in the treatment of urinary tract infections, recurrent pharyngeal tonsillitis, acute otitis media and acute exacerbation of chronic bronchitis. There were also differences in the dosing regimens, length of treatment and use of diagnostic techniques.</description><identifier>ISSN: 0036-5548</identifier><identifier>ISSN: 1651-1980</identifier><identifier>EISSN: 1651-1980</identifier><identifier>DOI: 10.1080/00365540210147624</identifier><identifier>PMID: 12238578</identifier><identifier>CODEN: SJIDB7</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>80 and over ; Acute Disease ; Adolescent ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents - therapeutic use ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antibiotics: therapeutic use ; Biological and medical sciences ; Bronchitis ; Child ; Child, Preschool ; Clinical Medicine ; Denmark ; Drug Prescriptions - statistics & numerical data ; Drug Utilization - standards ; Drug Utilization - trends ; Drug: statistics & numerical data ; Family ; Family Practice - standards ; Family Practice - trends ; Female ; Health Care Surveys ; Human ; Humans ; Infectious Medicine ; Infektionsmedicin ; Klinisk medicin ; Male ; Medical and Health Sciences ; Medical sciences ; Medicin och hälsovetenskap ; Non-U.S. Gov't ; Norway ; Otitis Media - diagnosis ; Otitis Media - drug therapy ; Pharmacology. Drug treatments ; Physician's Practice Patterns: standards ; Physician's Practice Patterns: trends ; Physicians ; Physicians, Family ; Practice Patterns, Physicians' - standards ; Practice Patterns, Physicians' - trends ; Preschool ; Prescriptions ; Questionnaires ; Sinusitis - diagnosis ; Sinusitis - drug therapy ; Support ; Surveys and Questionnaires ; Sweden ; Tonsillitis - diagnosis ; Tonsillitis - drug therapy ; Urinary Tract Infections - diagnosis ; Urinary Tract Infections - drug therapy</subject><ispartof>Scandinavian journal of infectious diseases, 2002, Vol.34 (8), p.602-609</ispartof><rights>2002 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2002</rights><rights>2002 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c532t-888f792067e412f3f090d5198fa7e855c8f8ef7f0d339ef2478f3ed3f965a2f33</citedby><cites>FETCH-LOGICAL-c532t-888f792067e412f3f090d5198fa7e855c8f8ef7f0d339ef2478f3ed3f965a2f33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/00365540210147624$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/00365540210147624$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>230,314,780,784,885,4023,27922,27923,27924,59646,59752,60435,60541,61220,61255,61401,61436</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13904365$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12238578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://lup.lub.lu.se/record/114860$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Odenholt, Inga</creatorcontrib><creatorcontrib>Bylander-Groth, Anita</creatorcontrib><creatorcontrib>Frimodt-Möller, Niels</creatorcontrib><creatorcontrib>Rokstad, Kirsten Skinlo</creatorcontrib><creatorcontrib>Mölstad, Sigvard</creatorcontrib><title>Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study</title><title>Scandinavian journal of infectious diseases</title><addtitle>Scand J Infect Dis</addtitle><description>There has been a dramatic increase in the prevalence of antibiotic-resistant bacteria worldwide. In the Scandinavian countries at least 90% of total antibiotic use relates to outpatients and therefore it has become increasingly important to know the antibiotic prescription pattern of general practitioners (GPs) in order to implement and monitor changes in antibiotic prescribing. The aim of the present study was to evaluate the prescription patterns of GPs in Denmark, Norway and Sweden. In order to achieve a reasonable comparison, a questionnaire consisting of 7 case reports concerning upper and lower respiratory tract infections, urinary tract infections and skin and soft tissue infections was sent to 1,000 GPs in the 3 countries. In general, the guidelines for the treatment of bacterial infections in the individual countries were followed by the responders. In all 3 countries, penicillin V was still the drug most frequently used in upper and lower respiratory tract infections. The greatest difference in prescribing patterns among the countries was seen in the treatment of urinary tract infections, recurrent pharyngeal tonsillitis, acute otitis media and acute exacerbation of chronic bronchitis. There were also differences in the dosing regimens, length of treatment and use of diagnostic techniques.</description><subject>80 and over</subject><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antibiotics: therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Bronchitis</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Clinical Medicine</subject><subject>Denmark</subject><subject>Drug Prescriptions - statistics & numerical data</subject><subject>Drug Utilization - standards</subject><subject>Drug Utilization - trends</subject><subject>Drug: statistics & numerical data</subject><subject>Family</subject><subject>Family Practice - standards</subject><subject>Family Practice - trends</subject><subject>Female</subject><subject>Health Care Surveys</subject><subject>Human</subject><subject>Humans</subject><subject>Infectious Medicine</subject><subject>Infektionsmedicin</subject><subject>Klinisk medicin</subject><subject>Male</subject><subject>Medical and Health Sciences</subject><subject>Medical sciences</subject><subject>Medicin och hälsovetenskap</subject><subject>Non-U.S. Gov't</subject><subject>Norway</subject><subject>Otitis Media - diagnosis</subject><subject>Otitis Media - drug therapy</subject><subject>Pharmacology. Drug treatments</subject><subject>Physician's Practice Patterns: standards</subject><subject>Physician's Practice Patterns: trends</subject><subject>Physicians</subject><subject>Physicians, Family</subject><subject>Practice Patterns, Physicians' - standards</subject><subject>Practice Patterns, Physicians' - trends</subject><subject>Preschool</subject><subject>Prescriptions</subject><subject>Questionnaires</subject><subject>Sinusitis - diagnosis</subject><subject>Sinusitis - drug therapy</subject><subject>Support</subject><subject>Surveys and Questionnaires</subject><subject>Sweden</subject><subject>Tonsillitis - diagnosis</subject><subject>Tonsillitis - drug therapy</subject><subject>Urinary Tract Infections - diagnosis</subject><subject>Urinary Tract Infections - drug therapy</subject><issn>0036-5548</issn><issn>1651-1980</issn><issn>1651-1980</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS0EokvhB3BBucBtwY7txAEuS4GCtBJFhbM1ccbUVdZebIfV_nscdqFCSOUwsqz53tPMPEIeM_qcUUVfUMobKQWtGWWibWpxhyxYI9mSdYreJYu5vyyAOiEPUrqmlIqG0_vkhNU1V7JVCxLfOmsxojeYKuerlc-udyE7U11ETCaWn_9WXUDOGH2q3mDeIfrqHD1GGAsEJrvsQvn-Mrg04Afn4YeDl9Wq-jxhmrseXMTqMk_D_iG5Z2FM-Oj4npKv7999OfuwXH86_3i2Wi-N5HVeKqVs29W0aVGw2nJLOzrIspmFFpWURlmFtrV04LxDW4tWWY4Dt10jofD8lKwPvmmH26nX2-g2EPc6gNPjtC3Vl9IJdTmipF3Ta26U0mJoUPcorTZdD0b0jWoBi92zg902hu_zVnrjksFxBI9hSrotKfBy6_-CTDWsE3IG2QE0MaQU0f4ZkVE9B6z_CbhonhzNp36Dw43imGgBnh4BSAZGG8Ebl2443lFRTAv3-sA5b0PcwC7EcdAZ9mOIv0X8tjle_SW_QhjzlYGI-jpM0Zdgb9niJ0Rv02k</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Odenholt, Inga</creator><creator>Bylander-Groth, Anita</creator><creator>Frimodt-Möller, Niels</creator><creator>Rokstad, Kirsten Skinlo</creator><creator>Mölstad, Sigvard</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D95</scope></search><sort><creationdate>2002</creationdate><title>Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study</title><author>Odenholt, Inga ; Bylander-Groth, Anita ; Frimodt-Möller, Niels ; Rokstad, Kirsten Skinlo ; Mölstad, Sigvard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c532t-888f792067e412f3f090d5198fa7e855c8f8ef7f0d339ef2478f3ed3f965a2f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>80 and over</topic><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antibiotics: therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Bronchitis</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Clinical Medicine</topic><topic>Denmark</topic><topic>Drug Prescriptions - statistics & numerical data</topic><topic>Drug Utilization - standards</topic><topic>Drug Utilization - trends</topic><topic>Drug: statistics & numerical data</topic><topic>Family</topic><topic>Family Practice - standards</topic><topic>Family Practice - trends</topic><topic>Female</topic><topic>Health Care Surveys</topic><topic>Human</topic><topic>Humans</topic><topic>Infectious Medicine</topic><topic>Infektionsmedicin</topic><topic>Klinisk medicin</topic><topic>Male</topic><topic>Medical and Health Sciences</topic><topic>Medical sciences</topic><topic>Medicin och hälsovetenskap</topic><topic>Non-U.S. Gov't</topic><topic>Norway</topic><topic>Otitis Media - diagnosis</topic><topic>Otitis Media - drug therapy</topic><topic>Pharmacology. Drug treatments</topic><topic>Physician's Practice Patterns: standards</topic><topic>Physician's Practice Patterns: trends</topic><topic>Physicians</topic><topic>Physicians, Family</topic><topic>Practice Patterns, Physicians' - standards</topic><topic>Practice Patterns, Physicians' - trends</topic><topic>Preschool</topic><topic>Prescriptions</topic><topic>Questionnaires</topic><topic>Sinusitis - diagnosis</topic><topic>Sinusitis - drug therapy</topic><topic>Support</topic><topic>Surveys and Questionnaires</topic><topic>Sweden</topic><topic>Tonsillitis - diagnosis</topic><topic>Tonsillitis - drug therapy</topic><topic>Urinary Tract Infections - diagnosis</topic><topic>Urinary Tract Infections - drug therapy</topic><toplevel>online_resources</toplevel><creatorcontrib>Odenholt, Inga</creatorcontrib><creatorcontrib>Bylander-Groth, Anita</creatorcontrib><creatorcontrib>Frimodt-Möller, Niels</creatorcontrib><creatorcontrib>Rokstad, Kirsten Skinlo</creatorcontrib><creatorcontrib>Mölstad, Sigvard</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Lunds universitet</collection><jtitle>Scandinavian journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Odenholt, Inga</au><au>Bylander-Groth, Anita</au><au>Frimodt-Möller, Niels</au><au>Rokstad, Kirsten Skinlo</au><au>Mölstad, Sigvard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study</atitle><jtitle>Scandinavian journal of infectious diseases</jtitle><addtitle>Scand J Infect Dis</addtitle><date>2002</date><risdate>2002</risdate><volume>34</volume><issue>8</issue><spage>602</spage><epage>609</epage><pages>602-609</pages><issn>0036-5548</issn><issn>1651-1980</issn><eissn>1651-1980</eissn><coden>SJIDB7</coden><abstract>There has been a dramatic increase in the prevalence of antibiotic-resistant bacteria worldwide. In the Scandinavian countries at least 90% of total antibiotic use relates to outpatients and therefore it has become increasingly important to know the antibiotic prescription pattern of general practitioners (GPs) in order to implement and monitor changes in antibiotic prescribing. The aim of the present study was to evaluate the prescription patterns of GPs in Denmark, Norway and Sweden. In order to achieve a reasonable comparison, a questionnaire consisting of 7 case reports concerning upper and lower respiratory tract infections, urinary tract infections and skin and soft tissue infections was sent to 1,000 GPs in the 3 countries. In general, the guidelines for the treatment of bacterial infections in the individual countries were followed by the responders. In all 3 countries, penicillin V was still the drug most frequently used in upper and lower respiratory tract infections. The greatest difference in prescribing patterns among the countries was seen in the treatment of urinary tract infections, recurrent pharyngeal tonsillitis, acute otitis media and acute exacerbation of chronic bronchitis. There were also differences in the dosing regimens, length of treatment and use of diagnostic techniques.</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>12238578</pmid><doi>10.1080/00365540210147624</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5548 |
| ispartof | Scandinavian journal of infectious diseases, 2002, Vol.34 (8), p.602-609 |
| issn | 0036-5548 1651-1980 1651-1980 |
| language | eng |
| recordid | cdi_pubmed_primary_12238578 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | 80 and over Acute Disease Adolescent Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antibiotics: therapeutic use Biological and medical sciences Bronchitis Child Child, Preschool Clinical Medicine Denmark Drug Prescriptions - statistics & numerical data Drug Utilization - standards Drug Utilization - trends Drug: statistics & numerical data Family Family Practice - standards Family Practice - trends Female Health Care Surveys Human Humans Infectious Medicine Infektionsmedicin Klinisk medicin Male Medical and Health Sciences Medical sciences Medicin och hälsovetenskap Non-U.S. Gov't Norway Otitis Media - diagnosis Otitis Media - drug therapy Pharmacology. Drug treatments Physician's Practice Patterns: standards Physician's Practice Patterns: trends Physicians Physicians, Family Practice Patterns, Physicians' - standards Practice Patterns, Physicians' - trends Preschool Prescriptions Questionnaires Sinusitis - diagnosis Sinusitis - drug therapy Support Surveys and Questionnaires Sweden Tonsillitis - diagnosis Tonsillitis - drug therapy Urinary Tract Infections - diagnosis Urinary Tract Infections - drug therapy |
| title | Differences in Antibiotic Prescribing Patterns Between General Practitioners in Scandinavia: A Questionnaire Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T16%3A27%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Differences%20in%20Antibiotic%20Prescribing%20Patterns%20Between%20General%20Practitioners%20in%20Scandinavia:%20A%20Questionnaire%20Study&rft.jtitle=Scandinavian%20journal%20of%20infectious%20diseases&rft.au=Odenholt,%20Inga&rft.date=2002&rft.volume=34&rft.issue=8&rft.spage=602&rft.epage=609&rft.pages=602-609&rft.issn=0036-5548&rft.eissn=1651-1980&rft.coden=SJIDB7&rft_id=info:doi/10.1080/00365540210147624&rft_dat=%3Cproquest_pubme%3E72103548%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=18619458&rft_id=info:pmid/12238578&rfr_iscdi=true |