Sex Difference of Urinary Osmolality in German Children

Background/Aims: Origin of sex difference in urinary osmolality. Methods: In 495 healthy children aged 4.0–14.9 years participating in the DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) study (247 boys, 248 girls), the water intake recorded in 24-hour weighed dietary record...

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Veröffentlicht in:American journal of nephrology 2002-07, Vol.22 (4), p.352-355
Hauptverfasser: Ebner, Arno, Manz, Friedrich
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container_title American journal of nephrology
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creator Ebner, Arno
Manz, Friedrich
description Background/Aims: Origin of sex difference in urinary osmolality. Methods: In 495 healthy children aged 4.0–14.9 years participating in the DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) study (247 boys, 248 girls), the water intake recorded in 24-hour weighed dietary records along with urinary volume, osmolality and free water reserve in 24-hour urine samples from the same day as the dietary record were determined. Results: Boys showed a significantly higher energy intake, total water intake, urinary osmolality and osmolar load than girls but no increase in urinary volume. When referred to energy intake, mean urinary volume and mean free water reserve were significantly higher in girls than boys. Girls could have a preference for food with a higher water density and lower non-renal water losses. Conclusion: German girls of the DONALD study displayed a lower urinary osmolality than German boys due to a relatively higher urinary volume. The sex difference could be caused by a higher water density of the ingested food (ml/kcal) and a lower insensible water loss (ml/kcal) in girls than boys.
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Methods: In 495 healthy children aged 4.0–14.9 years participating in the DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) study (247 boys, 248 girls), the water intake recorded in 24-hour weighed dietary records along with urinary volume, osmolality and free water reserve in 24-hour urine samples from the same day as the dietary record were determined. Results: Boys showed a significantly higher energy intake, total water intake, urinary osmolality and osmolar load than girls but no increase in urinary volume. When referred to energy intake, mean urinary volume and mean free water reserve were significantly higher in girls than boys. Girls could have a preference for food with a higher water density and lower non-renal water losses. Conclusion: German girls of the DONALD study displayed a lower urinary osmolality than German boys due to a relatively higher urinary volume. 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The sex difference could be caused by a higher water density of the ingested food (ml/kcal) and a lower insensible water loss (ml/kcal) in girls than boys.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>12169867</pmid><doi>10.1159/000065226</doi><tpages>4</tpages></addata></record>
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subjects Adolescent
Analysis. Health state
Biological and medical sciences
Child
Child, Preschool
Clinical Study
Drinking - physiology
Energy Intake - physiology
Epidemiology
Female
General aspects
Germany
Humans
Male
Medical sciences
Osmolar Concentration
Public health. Hygiene
Public health. Hygiene-occupational medicine
Sex Factors
Time Factors
Urine - physiology
Urodynamics
title Sex Difference of Urinary Osmolality in German Children
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