Ketogenic diet: does acetone stop seizures?

The mechanism of action of the ketogenic diet, a therapy for refractory epilepsy, is unknown. Our hypothesis is that acetone, one of three ketones elevated by the ketogenic diet, is directly responsible for the diet's anticonvulsant effects. This study examined the basic concepts of this hypoth...

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Veröffentlicht in:	Medical science monitor 2002-08, Vol.8 (8), p.HY19
Hauptverfasser:	Likhodii, Sergei S, Burnham, W McIntyre
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetone - administration & dosage Acetone - therapeutic use Animals Anticonvulsants - administration & dosage Anticonvulsants - therapeutic use Cerebrospinal Fluid - chemistry Convulsants - pharmacology Diet Epilepsy - diet therapy Epilepsy - drug therapy Fasting Humans Ketones - metabolism Magnetic Resonance Spectroscopy Male Pentylenetetrazole - pharmacology Rats Rats, Wistar Seizures - chemically induced
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