Contribution of the NQO1 and GSTT1 Polymorphisms to Lung Adenocarcinoma Susceptibility

Lung adenocarcinoma has replaced squamous cell lung carcinomaas the most frequent histological subtype in lung cancers. However, genetic factors that affect cancer susceptibility are much less understood in adenocarcinoma than in squamous cell carcinoma. In this study, polymorphisms in five genes in...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2002-08, Vol.11 (8), p.730-738
Hauptverfasser:	SUNAGA, Noriaki, KOHNO, Takashi, YANAGITANI, Noriko, SUGIMURA, Haruhiko, KUNITOH, Hideo, TAMURA, Tomohide, TAKEI, Yoshikazu, TSUCHIYA, Satoshi, SAITO, Ryusei, YOKOTA, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - etiology Adenocarcinoma - genetics Adult Biological and medical sciences Carcinogens - metabolism Carcinoma, Non-Small-Cell Lung - etiology Carcinoma, Non-Small-Cell Lung - genetics Case-Control Studies DNA Damage Female Genetic Predisposition to Disease Genotype Glutathione Transferase - genetics Glutathione Transferase - pharmacology Humans Lung Neoplasms - etiology Lung Neoplasms - genetics Male Medical sciences Middle Aged Odds Ratio Pneumology Polymorphism, Genetic Quinone Reductases - genetics Quinone Reductases - pharmacology Risk Factors Smoking - adverse effects Tumors of the respiratory system and mediastinum
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