Absolute Requirement of Spermidine for Growth and Cell Cycle Progression of Fission Yeast (Schizosaccharomyces pombe)

Schizosaccharomyces pombe cells that cannot synthesize spermidine or spermine because of a deletion-insertion in the gene coding for S-adenosylmethionine decarboxylase (Δspe2) have an absolute requirement for spermidine for growth. Flow cytometry studies show that in the absence of spermidine an ove...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2002-08, Vol.99 (16), p.10330-10334
Hauptverfasser:	Chattopadhyay, Manas K., Tabor, Celia White, Tabor, Herbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins Adenosylmethionine Decarboxylase - genetics Adenosylmethionine Decarboxylase - metabolism Animal cells Biochemistry Biological Sciences Cell cycle Cell Cycle - drug effects Cell division Cell Division - drug effects Cell growth Cell nucleus Cell walls Cellular biology DNA, Fungal - drug effects DNA, Fungal - metabolism Dose-Response Relationship, Drug Interphase Polyamines Schizosaccharomyces - cytology Schizosaccharomyces - drug effects Schizosaccharomyces - genetics Schizosaccharomyces - growth & development Spermidine - pharmacology Yeast Yeasts
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