Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers

Microsatellite instability (MSI) within coding regions causes frameshift mutations (FSMs). This type of mutation may inactivate tumor suppressor genes in cancers with frequent MSI (MSI-H cancers). To identify novel FSMs in gastric carcinogenesis in an unbiased and comprehensive manner, we screened f...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2002-07, Vol.62 (13), p.3641-3645
Hauptverfasser:	MORI, Yuriko, SATO, Fumiaki, JING YIN, ZOU, Tong-Tong, LEGGETT, Barbara, YOUNG, Joanne, NUKIWA, Toshihiro, STINE, O. Colin, ABRAHAM, John M, SHIBATA, David, MELTZER, Stephen J, SELARU, Florin M, OLARU, Andreea, PERRY, Kellie, KIMOS, Martha C, TAMURA, Gen, MATSUBARA, Nagahide, WANG, Suna, YAN XU
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Colorectal Neoplasms - genetics Frameshift Mutation Gastroenterology. Liver. Pancreas. Abdomen Humans Medical sciences Microsatellite Repeats - genetics Stomach Neoplasms - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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