Changes in Microvessel Density As Assessed by CD34 Antibodies after Primary Chemotherapy in Human Breast Cancer

Background: Several papers have shown that quantitationof tumor angiogenesis in primary breast cancer by counting blood vessels gives an independent assessment of prognosis. The impact of chemotherapy ± endocrine therapy on the extent of angiogenesis is unknown. Methods: Matched pair histological tu...

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Veröffentlicht in:	Clinical cancer research 2002-06, Vol.8 (6), p.1816-1821
Hauptverfasser:	BOTTINI, Alberto, BERRUTI, Alfredo, SCARATTI, Lorena, BERTOLI, Giovanni, ALQUATI, Palmiro, DOGLIOTTI, Luigi, BERSIGA, Alessandra, BRIZZI, Maria Pia, ALLEVI, Giovanni, BOLSI, Giovanna, AGUGGINI, Sergio, BRUNELLI, Antonio, BETRI, Enrico, GENERALI, Daniele
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Monoclonal - metabolism Antigens, CD34 - immunology Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast Neoplasms - blood supply Breast Neoplasms - drug therapy Breast Neoplasms - pathology Chemotherapy Cyclophosphamide - administration & dosage Epirubicin - administration & dosage Female Fluorouracil - administration & dosage Humans Immunoenzyme Techniques Ki-67 Antigen - metabolism Medical sciences Methotrexate - administration & dosage Microcirculation Middle Aged Neoplasm Staging Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Pharmacology. Drug treatments Proto-Oncogene Proteins c-bcl-2 - metabolism Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Survival Rate Tamoxifen - administration & dosage Tumor Suppressor Protein p53 - metabolism
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