Evaluation of Fentanyl Transdermal Patches in Rabbits: Blood Concentrations and Physiologic Response

In the study reported here, we sought to evaluate transdermal fentanyl patches for their ability to achieve detectable plasma concentrations with minimal adverse effects in New Zealand White rabbits. Fentanyl patches were applied to the dorsum after removing hair either by clipping or by application...

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Veröffentlicht in:	Comparative medicine 2001-06, Vol.51 (3), p.239-244
Hauptverfasser:	Foley, Patricia L., Henderson, Andrea L., Bissonette, Eric A., Wimer, Gina R., Feldman, Sanford H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Analgesia - methods Analgesia - veterinary Analgesics, Opioid - administration & dosage Analgesics, Opioid - blood Analgesics, Opioid - toxicity Animals Female Fentanyl - administration & dosage Fentanyl - blood Fentanyl - toxicity Hair - growth & development Hair Removal Rabbits - blood Rabbits - physiology Respiration - drug effects
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