Clavosolides A and B, dimeric macrolides from the Philippines sponge Myriastra clavosa

A specimen of the sponge Myriastra clavosa from the Philippines contained two dimeric macrolides, clavosolides A and B. Clavosolide A is a symmetrical dimer, while clavosolide B is rendered unsymmetrical by the replacement of one of the methoxyl groups by a hydroxyl group. The structures of the clav...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2002-03, Vol.65 (3), p.386
Hauptverfasser:	Rao, M Rama, Faulkner, D John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, High Pressure Liquid Macrolides - chemistry Macrolides - isolation & purification Molecular Structure Nuclear Magnetic Resonance, Biomolecular Philippines Porifera - chemistry Stereoisomerism
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description	A specimen of the sponge Myriastra clavosa from the Philippines contained two dimeric macrolides, clavosolides A and B. Clavosolide A is a symmetrical dimer, while clavosolide B is rendered unsymmetrical by the replacement of one of the methoxyl groups by a hydroxyl group. The structures of the clavosolides were elucidated by interpretation of spectroscopic data.
doi_str_mv	10.1021/np010495l
format	Article
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subjects	Animals Chromatography, High Pressure Liquid Macrolides - chemistry Macrolides - isolation & purification Molecular Structure Nuclear Magnetic Resonance, Biomolecular Philippines Porifera - chemistry Stereoisomerism
title	Clavosolides A and B, dimeric macrolides from the Philippines sponge Myriastra clavosa
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