Acute lung injury: Functional genomics and genetic susceptibility

Initiated by numerous factors, acute lung injury is marked by epithelial and endothelial cell perturbation and inflammatory cell influx that leads to surfactant disruption, pulmonary edema, and atelectasis. This syndrome has been associated with a myriad of mediators including cytokines, oxidants, a...

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Veröffentlicht in:	Chest 2002-03, Vol.121 (3), p.70S-75S
Hauptverfasser:	LEIKAUF, George D, MCDOWELL, Susan A, WESSELKAMPER, Scott C, HARDIE, William D, LEIKAUF, John E, KORFHAGEN, Thomas R, PROWS, Daniel R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Animals Aquaporin 1 Aquaporins - genetics Biological and medical sciences Chromosome Mapping Environmental Exposure Gene Expression Genetic Linkage Genetic Predisposition to Disease Lung - pathology Medical sciences Mice Mice, Inbred Strains Mice, Transgenic Nickel Oligonucleotide Array Sequence Analysis Ozone Pneumology Polytetrafluoroethylene Proteolipids - genetics Pulmonary Surfactants - genetics Quantitative Trait, Heritable Respiratory Distress Syndrome, Adult - etiology Respiratory Distress Syndrome, Adult - genetics Respiratory Distress Syndrome, Adult - pathology Respiratory system : syndromes and miscellaneous diseases Risk Factors Transforming Growth Factor alpha - genetics Transforming Growth Factor alpha - physiology
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