Vitamin C and quercetin modulate DNA-damaging effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)

The effects of natural compounds, vitamin C and quercetin, present in fruits and vegetables, on the DNA damaging activity of a food carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) were examined using the comet assay. Vitamin C, at a concentration of 50 microM, inhibited MNNG-induced DNA...

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Veröffentlicht in:	Plant foods for human nutrition (Dordrecht) 2002, Vol.57 (1), p.53-61
Hauptverfasser:	BŁASIAK, J, TRZECIAK, A, GASIOROWSKA, A, DRZEWOSKI, J, MAŁECKA-PANAS, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants - pharmacology Ascorbic Acid - pharmacology Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Copper - pharmacology DNA Damage - drug effects Foods and miscellaneous Fruit - chemistry General pharmacology Humans Hydrogen Peroxide - pharmacology Lymphocytes - chemistry Medical sciences Methylnitronitrosoguanidine - pharmacology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Quercetin - pharmacology Tumors Vegetables - chemistry
Online-Zugang:	Volltext
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